The effect of calcium gluconate administration during cardiopulmonary bypass on hemodynamic variables in infants undergoing open-heart surgery

Faritous, Seyedeh Zahra; Zaree, Saeed Rajabzade; Morshedizad, Zohreh; Jalali, Amir Hossein; Mahani, Soha Mehrabi; Gholampour, Maziar

doi:10.1186/s43044-022-00266-w

Cited by 3 publications

(4 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…No patients had any respiratory symptoms. The minimum cross-sectional tracheal area was significantly decreased at 6M and 12M after tracheostomy compared to BL (BL: 285 [68] mm 2 ; 6M: 267 [70] mm 2 , P < 0.01 vs. BL; 12M: 269 [68] mm 2 , P < 0.01 vs. BL) (Figure 3A). Of the 77 analyzed patients, tracheal stenosis was observed in 55 (71.4%) patients by 11.9% (9.4%) at 6M, and in 49 (63.6%) patients by 12.2% (8.8%) at 12M.…”

Section: Resultsmentioning

confidence: 99%

“…Calcium is an important inotrope in an infant with RV dysfunction. Prior work has demonstrated that infants treated with intravenous calcium following cardiopulmonary bypass demonstrated significant improvements in cardiac output and mean systemic blood pressure compared to infants who did not receive calcium (68). Similarly, multiple case series attest to the incidence of myocardial dysfunction in infants manifesting nutrition-mediated hypocalcemia (69, 70).…”

Section: Inotropic and Vasoactive Agentsmentioning

confidence: 98%

“…Ress and Dudley (1998)(68) reported the role of oxygen therapy, especially oxygen or oxygen concentrators for patients being treated at home. Employing a recently designed polymer of poly[1-(trimethylsilyl)-1-propyne] with an oxygen permeability of 61 × 10 cm 3 (STP) cm/cm 2 s cmHg, which itself is 17 times greater than those of the membrane material of traditional concentrators, Akutsu et al in 1990 built a small, light-weight oxygen concentrator.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Respiratory Support: Clinical Applications and the Novel Future

2024

Frontiers Research Topics

View full text Add to dashboard Cite

Frontiers is more than just an open access publisher of scholarly articles: it is a pioneering approach to the world of academia, radically improving the way scholarly research is managed. The grand vision of Frontiers is a world where all people have an equal opportunity to seek, share and generate knowledge. Frontiers provides immediate and permanent online open access to all its publications, but this alone is not enough to realize our grand goals. Frontiers journal seriesThe Frontiers journal series is a multi-tier and interdisciplinary set of openaccess, online journals, promising a paradigm shift from the current review, selection and dissemination processes in academic publishing. All Frontiers journals are driven by researchers for researchers; therefore, they constitute a service to the scholarly community. At the same time, the Frontiers journal series operates on a revolutionary invention, the tiered publishing system, initially addressing specific communities of scholars, and gradually climbing up to broader public understanding, thus serving the interests of the lay society, too. Dedication to qualityEach Frontiers article is a landmark of the highest quality, thanks to genuinely collaborative interactions between authors and review editors, who include some of the world's best academicians. Research must be certified by peers before entering a stream of knowledge that may eventually reach the public -and shape society; therefore, Frontiers only applies the most rigorous and unbiased reviews. Frontiers revolutionizes research publishing by freely delivering the most outstanding research, evaluated with no bias from both the academic and social point of view. By applying the most advanced information technologies, Frontiers is catapulting scholarly publishing into a new generation. What are Frontiers Research Topics?Frontiers Research Topics are very popular trademarks of the Frontiers journals series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Inotropic and Vasoactive Agentsmentioning

confidence: 98%

mentioning

confidence: 99%

See 1 more Smart Citation

Respiratory Support: Clinical Applications and the Novel Future

2024

Frontiers Research Topics

View full text Add to dashboard Cite

show abstract

“…Calcium is an important inotrope in an infant with RV dysfunction. Prior work has demonstrated that infants treated with intravenous calcium following cardiopulmonary bypass demonstrated significant improvements in cardiac output and mean systemic blood pressure compared to infants who did not receive calcium ( 68 ). Similarly, multiple case series attest to the incidence of myocardial dysfunction in infants manifesting nutrition-mediated hypocalcemia ( 69 , 70 ).…”

Section: Therapeutic Strategies For Rv Dysfunction During Pardsmentioning

confidence: 99%

Cardiac dysfunction in severe pediatric acute respiratory distress syndrome: the right ventricle in search of the right therapy

Webb,

Burton,

Manchikalapati

et al. 2023

Front. Med.

View full text Add to dashboard Cite

Severe acute respiratory distress syndrome in children, or PARDS, carries a high risk of morbidity and mortality that is not fully explained by PARDS severity alone. Right ventricular (RV) dysfunction can be an insidious and often under-recognized complication of severe PARDS that may contribute to its untoward outcomes. Indeed, recent evidence suggest significantly worse outcomes in children who develop RV failure in their course of PARDS. However, in this narrative review, we highlight the dearth of evidence regarding the incidence of and risk factors for PARDS-associated RV dysfunction. While we wish to draw attention to the absence of available evidence that would inform recommendations around surveillance and treatment of RV dysfunction during severe PARDS, we leverage available evidence to glean insights into potentially helpful surveillance strategies and therapeutic approaches.

show abstract

Perioperative Modulation of Left Ventricular Systolic Performance: A Retrospective Study on Ionized Calcium and Vitamin D in Cardiac Surgery Patients

Ștef,

Bodolea,

Bocșan

et al. 2024

JPM

View full text Add to dashboard Cite

Background: The perioperative impact of calcium and vitamin D on left ventricular (LV) performance during major cardiac surgery remains unexplored. We aimed to assess the relation of calcium and vitamin D measured at different time points with the LV ejection fraction (EF), and to investigate whether changes in EF correlate with postoperative outcomes. Methods: We enrolled 83 patients, in whom ionized calcium was measured before, during, and after surgery (until discharge), vitamin D preoperatively, and EF pre- and postoperatively at 24 h. The postoperative outcomes were cardiopulmonary bypass (CPB) time, aortic cross-clamp time, mechanical ventilation time, vasoactive inotropic score (VIS) (intraoperative, day 0, day 1), and ICU stay time. Results: The mean age was 64.9 ± 8.5 years, with 21 of the patients (25%) having an EF < 50%. The median change from preoperative to postoperative EF was −2.0 (−10.0–0.0) % (p < 0.001). At the baseline, the EF < 50% group had significantly lower preoperative vitamin D levels than the EF ≥ 50% group (p = 0.048). The calcium trend did not differ across the groups. Preoperative EF was significantly associated with CPB time (r = 0.22, p = 0.044) and aortic cross-clamp time (r = 0.24, p = 0.031). Postoperative EF was significantly and inversely associated with intraoperative VIS (r = −0.28, p = 0.009), VIS day 0 (r = −0.25, p = 0.020), VIS day 1 (r = −0.23, p = 0.036), and ICU length of stay (r = −0.22, p = 0.047). Finally, the change in ejection fraction was significantly and inversely associated with CPB time (r = −0.23, p = 0.037), aortic cross-clamp time (r = −0.22, p = 0.044), intraoperative VIS (r = −0.42, p < 0.001), VIS day 0 (r = −0.25, p = 0.024), mechanical ventilation time (r = −0.22, p = 0.047), and ICU length of stay (r = −0.23, p = 0.039). Conclusions: The fluctuations in perioperative ionized calcium levels were not associated with the evolution of LVEF, although preoperative vitamin D levels may affect those with low EF. Correspondingly, a reduced EF significantly impacted all the studied postoperative outcomes. Further investigation into biomarkers affecting cardiac inotropic function is warranted to better understand their significance.

show abstract

The effect of calcium gluconate administration during cardiopulmonary bypass on hemodynamic variables in infants undergoing open-heart surgery

Cited by 3 publications

References 38 publications

Respiratory Support: Clinical Applications and the Novel Future

Respiratory Support: Clinical Applications and the Novel Future

Cardiac dysfunction in severe pediatric acute respiratory distress syndrome: the right ventricle in search of the right therapy

Perioperative Modulation of Left Ventricular Systolic Performance: A Retrospective Study on Ionized Calcium and Vitamin D in Cardiac Surgery Patients

Contact Info

Product

Resources

About