The effect of calcium supplementation in people under 35 years old: A systematic review and meta-analysis of randomized controlled trials

Liu, Yupeng; Le, Siyu; Liu, Yi; Jiang, Huinan; Ruan, Binye; Huang, Yufeng; Ao, Xuemei; Shi, Xudong; Fu, Xiaoyi; Wang, Shuran

doi:10.7554/elife.79002

Cited by 10 publications

(7 citation statements)

References 62 publications

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“…Sufficient calcium intake is important for bone health, dental health, muscle function, and more [ 114 , 115 , 116 , 117 ]. Sufficient calcium intake is especially necessary in children and adolescents for the attainment of optimal peak bone mass.…”

Section: Question Four: What Is Your Preferred Source Of Calcium?mentioning

confidence: 99%

Nutritional Assessment of the Symptomatic Patient on a Plant-Based Diet: Seven Key Questions

Plotnikoff¹,

Dobberstein²,

Raatz

2023

Nutrients

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Plant-based diets, both vegan and vegetarian, which emphasize grains, vegetables, fruits, legumes, nuts, and seeds are increasingly popular for health as well as financial, ethical, and religious reasons. The medical literature clearly demonstrates that whole food plant-based diets can be both nutritionally sufficient and medically beneficial. However, any person on an intentionally restrictive, but poorly-designed diet may predispose themselves to clinically-relevant nutritional deficiencies. For persons on a poorly-designed plant-based diet, deficiencies are possible in both macronutrients (protein, essential fatty acids) and micronutrients (vitamin B12, iron, calcium, zinc, and vitamin D). Practitioner evaluation of symptomatic patients on a plant-based diet requires special consideration of seven key nutrient concerns for plant-based diets. This article translates these concerns into seven practical questions that all practitioners can introduce into their patient assessments and clinical reasoning. Ideally, persons on plant-based diets should be able to answer these seven questions. Each serves as a heuristic prompt for both clinician and patient attentiveness to a complete diet. As such, these seven questions support increased patient nutrition knowledge and practitioner capacity to counsel, refer, and appropriately focus clinical resources.

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Section: Question Four: What Is Your Preferred Source Of Calcium?mentioning

confidence: 99%

Nutritional Assessment of the Symptomatic Patient on a Plant-Based Diet: Seven Key Questions

Plotnikoff¹,

Dobberstein²,

Raatz

2023

Nutrients

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“…Unabhängig von der gesetzlichen Unterscheidung zwischen Mineral-und Heilwässern handelt es sich in beiden Fällen um Flüssigkeiten mit besonderen physikochemischen Eigenschaften: Der Gehalt und die Relation der im Wasser gelösten Kationen und Anionen wird bestimmt von den geologischen Gegebenheiten am Quellort [25,26]. Jede Wassersorte weist daher eine spezifische Mineralisierung auf, so dass sich die Wässer auch aus ernährungsphysiologischer Sicht voneinander unterscheiden [12,13,[27][28][29] Blick auf das Erreichen der peak bone mass ist dieser Wert möglicherweise zu niedrig angesetzt, wie Studien zur maximalen Calciumretention nahelegen [43][44][45]. Expertengremien der WHO/FAO sowie des US-amerikanischen Institute of Medicine (IOM) empfehlen für Jugendliche eine höhere Zufuhr von 1300 mg Calcium pro Tag [42].…”

Section: Heilwasserunclassified

Ossäre Bedeutung von Mineral- und Heilwässern: Physiologie und epidemiologische Evidenz

Ströhle,

Hahn

2023

Osteologie

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ZusammenfassungMineral- und Heilwässer zeichnen sich durch eine sortenspezifische Zusammensetzung aus, so dass sich die Wässer auch ausernährungsphysiologischer Sicht voneinander unterscheiden. Viele Mineral- und Heilwässer bilden eine quantitativ bedeutsame Quelle für gut bioverfügbares Calcium und Magnesium. Calciumreiche Wässer stellen somit eine günstige Alternative zum gut löslichen Calciumcitrat dar, wie es in der Leitlinie der Bone Health & Osteoporosis Foundation bei Achlorhydrie oder eingeschränkter Magensäureproduktion (z. B. Therapie mit Protonenpumpeninhibitoren) als Calciumquelle empfohlen wird. Calciumwässer senken den Serumspiegel an Parathormon ähnlich stark wie Calcium aus Milch oder Supplementen mit einem äquivalenten Gehalt des Mineralstoffs. Damit verbunden ist bei alkalischen Calciumwässern eine Hemmung der Knochenresorption. Auch senken bikarbonatreiche Wässer die renale Säurelast sowie die Calciumverluste über den Urin. Ungeklärt ist der Einfluss der Wässer auf die Calciumbilanz und das Frakturrisiko. Der Natrium- und Kaliumgehalt der meisten Wässer ist zu gering, um den Knochenstoffwechsel nennenswert beeinflussen zu können. Auch üben Wässer mit moderatem Fluoridgehalt (0,70-1,0 mg/l) keinen, von anderen Nahrungsfaktoren (Calcium, Protein) unabhängigen Einfluss auf die Mikrostruktur der Knochen aus.

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“…For the rapid bone loss of osteoporosis patients, the adult calcium supplement dose is about 1000 mg/d and it should be taken continuously for a long time. At the same time, vitamin D should be supplemented to promote calcium absorption, and it is suggested that the blood calcium and urine calcium levels of patients should be monitored regularly [75].…”

Section: Reasonable Treatment Of Fracturementioning

confidence: 99%

Progress in Prevention and Treatment of Acute Bone Loss in Orthopedics

Wang,

Wu,

Wang

et al. 2023

International Journal of Endocrinology

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Orthopedic patients need to perform limb immobilization for several days to several weeks due to fracture or other special circumstances. When the function of a certain part or the whole body is restricted, the activity of osteoclasts will be enhanced and its life activity will surpass that of osteoblasts, so local or even whole body bone loss will occur. Acute bone loss usually occurs within a few weeks after the immobilization of limbs. At this stage, the patient’s bone mass will decrease sharply, and the patient is prone to osteoporotic refracture. After that, the bone mass will gradually recover, but the speed of bone formation and bone absorption is difficult to reach a balanced state, and the bone mass of patients will continue to decline after it has recovered to a certain degree. After acute progressive bone loss, a large number of bones were lost and the strength of bones decreased. It is often difficult to recover to the level before fracture for a long time, which undoubtedly increases the risk of osteoporosis and related refractures. According to this common phenomenon of bone loss, clinical treatment varies greatly. After a series of research and practice, clinicians summed up some rules and put forward some feasible suggestions, thus strengthening clinicians’ understanding of the treatment of acute bone loss, effectively improving the treatment effect of acute bone loss, having far-reaching significance for preventing and treating osteoporosis, reducing the risk of fracture, and improving the long-term prognosis of patients.

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The effect of calcium supplementation in people under 35 years old: A systematic review and meta-analysis of randomized controlled trials

Cited by 10 publications

References 62 publications

Nutritional Assessment of the Symptomatic Patient on a Plant-Based Diet: Seven Key Questions

Nutritional Assessment of the Symptomatic Patient on a Plant-Based Diet: Seven Key Questions

Ossäre Bedeutung von Mineral- und Heilwässern: Physiologie und epidemiologische Evidenz

Progress in Prevention and Treatment of Acute Bone Loss in Orthopedics

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