The Effect Of Chemotherapy On Malnutrition In Geriatric Group With Metastatic Colorectal Cancer

Abstract

Objective: Malnutrition in geriatric patients with colorectal cancer (CRC), especially those who received chemotherapy (CT), is a frequent condition. The aim of this study was to determine the effect of CT on malnutrition in patients with geriatric metastatic CRC (mCRC). Methods:A total of 136 patients aged 70 years and older, and diagnosed with mCRC, were enrolled in the study. The nutritional status of the patients was evaluated with the Nutritional Risk Score-2002 before CT and after one CT course.Results: The median follow-up time was 18.5 months. The median age was 74. The ECOG performance score of all patients was 0 or 1. 62.5% had liver metastasis, 26% had lung metastasis, 25% peritoneal metastasis, and 8% bone metastasis. It was determined that 17.3% of patients were malnurished, and 24.6% had a risk of malnutrition. 49.4% of patients with pre-CT weight loss have begun. The average weight loss before the first CT was 12.1%, and the incidence of malnutrition after one course of CT was 46.4% (p=0.001). Conclusion:Malnutrition is frequently observed in patients with geriatric mCRC, and even a single course of CT increases malnutrition in patients.