The Effect of Chronic Disorders on Sleep in the Elderly

A study on sleep architecture in patients with chronic respiratory failure under long-term oxygen therapy—Focused on the influence of ventilatory failure (high CO<sub>2</sub>) elements on the patient’s sleep architecture

“…Colemen [26] et al reported that PLMD was observed in 3.5% of hypersomnia patients and this incidence was raised to 18% in such patients aged 65 or over. Since the incidence of PLMD is high in the patients with cerebrovascular disorder and myelopathy, damage to the inhibitory system between the central nerve and ventral horn cell that functions during sleep may be associated with decrease in the threshold of the disease onset [27]. Variance in sympathetic nerve activity in the pons and reticular formation seems to be associated with periodic onset of PLMD since the interval of muscle contraction matches the fluctuation of breathing, arterial and cerebrospinal fluid pressure, which is suppressed by sympathetic nerve system during sleep [28].…”

Can physical activity affect sleep disruption among the elderly with diabetes mellitus?

“…DM has prominent effects on sleep disturbances in the elderly [3]. Diabetic patients have sleep loss and sleep problems [11,13], which affect the quality of life and sleep [11].…”

“…Sleep disturbances are common among older adults [2,3], with a prevalence of 12-54 % [4]. Sleep disturbances frequently associate with existing chronic diseases [3], physical problems, and mental health [5,6]. Thus, medical conditions, medications, circadian rhythm changes, environmental hazards, and lifestyle changes [7,8] can increase the risk of sleep disruption in the elderly.…”

“…In human, adults need to sleep 7.0 and 8.4 h daily [1]. Sleep disturbances are common among older adults [2,3], with a prevalence of 12-54 % [4]. Sleep disturbances frequently associate with existing chronic diseases [3], physical problems, and mental health [5,6].…”

Research of Sleep Disorders in Patients with Acute Cerebral Infarction

“…[3][4][5][6] Some reports showed that SD can not only affect the cognitive function, life quality, physical and mental health, and recovery of patients' physiological functions, but also aggravate the risk of acute cerebral infarction, and at worst, induce the recurrence of acute cerebral infarction. 7 At present, the relationship between SD and cerebral infarction has been well described, but still not fully understood. Limited data are available in related research of the detailed classification in patients with both SD and acute cerebral infarction.…”