The Effect of Cigarette Smoking on Skin-Flap Survival in the Face Lift Patient

Rees, Thomas D.; Liverett, David M.; Guy, Cary L.

doi:10.1097/00006534-198406000-00009

Cited by 297 publications

(99 citation statements)

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“…Other researchers said that a preoperative blood pressure omore than 150/100 mmHg was associated with a 2.6-fold greater incidence of hematoma 16 . Intraoperative hypotension increased the risk of hematoma and attributed this to rebound hypertension 17,18 . A consensus from these articles is that blood pressure should be well controlled throughout the entire perioperative period.…”

Section: Discussionmentioning

confidence: 99%

A simple, novel technique for fixing Penrose drains in minor surgeries, with advantages for remote outpatient clinics: a retrospective comparison with conventional drain fixation in North Ibaraki, Japan

Shibuya

Matsumoto

Sasaki

et al. 2017

RRH

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A B S T R A C TIntroduction: In rural areas with few doctors, Penrose drains in minor surgeries for soft tissue trauma or small subcutaneous tumors are sometimes avoided, even though the drain would prevent hematoma, because of the limited availability of professional postsurgical care. The authors developed a simple fixation method for Penrose drains that can be used even in remote areas where a doctor is not present to remove the drain. A retrospective study was conducted to compare this new method of fixing Penrose drains with instances in which the Penrose drain was fixed to skin by conventional suturing. Methods: The medical records of patients who underwent minor surgeries using Penrose drains were reviewed. The surgeries were performed from April 2012 to March 2015 in remote outpatient clinics in Ibaraki Prefecture, Japan. The cases were divided © Y Shibuya, G Matsumoto, M Sasaki, K Sasaki, K Adachi, M Sekido 2017. A Licence to publish this material has been given to James Cook University, http://www.jcu.edu.au 2 into two groups: those using the new method, in which the Penrose drains were sewn onto the wound dressings and could be automatically removed while changing the dressing, and those in which the Penrose drains were conventionally fixed to the skin and removed one or several days after surgery by another doctor at the outpatient clinic. The rates of drain-related complications and of automatic drain removal (ie removal without a doctor's assistance) between the two groups were compared. Results: A total of 54 Penrose drains used for 48 lesions in 44 patients (25 men, 19 women) in the new-method group, and 36 Penrose drains for 25 lesions in 21 patients (12 men, 9 women) in the conventional-method (control) group were analyzed. All 54 Penrose drains in the new-method group were removed automatically, while none of the 36 drains in the control group were removed automatically. There were no drain-related complications, such as massive hematoma, retrograde infection, seroma, or drain breakage or straying, in any of the new-method or control cases.Conclusions: This new Penrose-drain fixation method is safe and is particularly suitable for minor surgeries in rural areas where there are no resident doctors. The wide use of this method for appropriate minor surgeries in doctorless rural areas has the potential to reduce surgical complications and the time burden for both patients and surgeons.

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Section: Discussionmentioning

confidence: 99%

A simple, novel technique for fixing Penrose drains in minor surgeries, with advantages for remote outpatient clinics: a retrospective comparison with conventional drain fixation in North Ibaraki, Japan

Shibuya

Matsumoto

Sasaki

et al. 2017

RRH

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“…Muitos autores relataram deficiências cicatriciais em fumantes [6][7][8][9][10] bem como aumentam as chances de hér-nias incisionais e de recidiva de hérnias [9][10] . Além disso, em fumantes, a possibilidade de isquemia de retalhos é também maior 7 .…”

Section: Discussão Discussão Discussão Discussão Discussãounclassified

“…Além disso, em fumantes, a possibilidade de isquemia de retalhos é também maior 7 . Galatz et al 23 observaram que, sob o efeito da nicotina, a fase inflamatória se estendeu por mais tempo e Machado 24 referiu que na cicatrização de bexigas, em ratos, encontrou menor reação inflamatória com menor nú-mero de neutrófilos.…”

Section: Discussão Discussão Discussão Discussão Discussãounclassified

A influência da nicotina na densidade de colágeno em cicatrizes cutâneas, em ratos

Biondo-Simões

Tetilla

Biondo-Simões

et al. 2009

Rev. Col. Bras. Cir.

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A influência da nicotina na densidade de colágeno em cicatrizes A influência da nicotina na densidade de colágeno em cicatrizes A influência da nicotina na densidade de colágeno em cicatrizes A influência da nicotina na densidade de colágeno em cicatrizes A influência da nicotina na densidade de colágeno em cicatrizes cutâneas, em ratos cutâneas, em ratos cutâneas, em ratos cutâneas, em ratos cutâneas, em ratosThe influence of nicotine on the density of collagen in cutaneous scars in rats The influence of nicotine on the density of collagen in cutaneous scars in rats The influence of nicotine on the density of collagen in cutaneous scars in rats The influence of nicotine on the density of collagen in cutaneous scars in rats The influence of nicotine on the density of collagen in cutaneous scars in rats Objetivo: Objetivo: Estudar a reação inflamatória e a deposição de colágeno na cicatrização de feridas cutâneas sob a influência da nicotina. Métodos: Métodos: Métodos: Métodos: Métodos: Analisaram-se as cicatrizes de feridas abdominais de ratos tratados com nicotina, 2 mg/kg/d, comparando-as às de ratos controle. O tratamento foi iniciado sete dias antes do ato operatório e mantido por sete ou 14 dias, no pós-operatório. Os cortes histológicos foram corados pela hematoxilina e eosina e neles por meio de escores estabelecidos, reconheceu-se a intensidade e o tipo da reação inflamatória. Cortes histológicos corados pelo Sirius Supra red F3BA permitiram reconhecer a densidade do colágeno. Resultados: Resultados: Resultados: Resultados: Resultados: Não houve diferença quanto à intensidade da reação inflamatória na análise de sete dias (p=0,165) e nem na de 14 dias (p=0,684). Pôde-se verificar que não existiu diferença significante na densidade de colágeno tipo I, na avaliação feita com sete dias (p=0,912) e com 14 dias (p=0,211). O grupo controle mostrava mais colágeno tipo III com sete dias (p=0,004), mas aos 14 não havia diferença significante (p=0,720). A quantificação do colágeno total, embora fosse maior no grupo controle, não o foi de forma significante em nenhum dos tempos estudados (p=0,103 aos sete e p=0,549 aos 14 dias). Conclusão:Conclusão: Conclusão: Conclusão: Conclusão: Não houve, nas cicatrizes dos animais tratados com nicotina, em relação aos controles, diferença quanto à intensidade do processo inflamatório, nem quanto à densidade do colágeno. . Vários estudos experimentais, realizados em diferentes condições, descreveram efeito inibitório da nicotina sobre a migração e diferenciação dos queratinócitos 11,12 , levando ao atraso da reepitelização 13 . Fang e Svoboda, estudando fibroblastos humanos, cultivados com diferentes concentrações de nicotina, observaram que existia inibição da diferenciação dos fibroblastos a miofibroblastos e atribuíram a isto a diminuição da contração das feridas 14 . São relatadas modificações citoplasmáticas, degeneração e inatividade dos fibroblastos [15][16][17] , além da diminuição do número destas células e da sua diferenciação 13,15,16,[18][19][20] . Estes efeitos for...

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“…[4][5][6][7][8] Smoking has also been shown to impair soft tissue wound healing in humans and in a number of animal models. [9][10][11][12][13][14][15] While no previous studies have examined the relationship between ligament healing and smoking, ligament healing represents a soft tissue wound repair response likely affected by exposure to cigarette smoke.…”

Section: Introductionmentioning

confidence: 99%

Effects of cigarette smoking on early medial collateral ligament healing in a mouse model

Gill¹,

Sandell²,

El-Zawawy³

et al. 2006

J. Orthop. Res.

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Cigarette smoking delays the healing process and increases morbidity associated with many common musculoskeletal disorders such as medial collateral ligament (MCL) injury. In the current study, a murine model of MCL healing was used to test the hypothesis that smoking impairs extracellular matrix synthesis after injury. Mice were divided into two groups, a nonsmoking control group and a group exposed to smoke for 2 months prior to surgical MCL injury. Mice were euthanized at 3 and 7 days after surgery. Subsequently, propidium iodine staining was used to quantify cellular density of injured and sham ligaments. Immunohistochemical staining and in situ hybridization to mRNA were used to detect proliferation, apoptosis, and type I collagen gene expression at the site of injury. Cell density increased significantly from baseline to 7 days after injury in control mice. In mice exposed to cigarette smoke, there was a significantly lower cellular density compared to controls at this time point ( p ¼ 0.01). There was no difference in proliferation between groups at the site of injury, and the low level of proliferation observed was not sufficient to account for the large increase in cell density by day 7. No evidence of apoptosis was observed in any of the groups at the site of injury. Type I collagen gene expression was higher in controls compared to smokers at day 7. Almost all of the cells in the substance of the injured MCL at day 7 were spindle-shaped and expressed type I collagen, suggesting that increased cell density from day 3 to day 7 represented an increase in ligament cells rather than an increased inflammatory response. We conclude that the decreased cellular density and type I collagen expression in the injured ligament of mice exposed to smoke begin to provide a cellular and molecular basis for delayed or deficient early healing in these animals. ß

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The Effect of Cigarette Smoking on Skin-Flap Survival in the Face Lift Patient

Cited by 297 publications

References 0 publications

A simple, novel technique for fixing Penrose drains in minor surgeries, with advantages for remote outpatient clinics: a retrospective comparison with conventional drain fixation in North Ibaraki, Japan

A simple, novel technique for fixing Penrose drains in minor surgeries, with advantages for remote outpatient clinics: a retrospective comparison with conventional drain fixation in North Ibaraki, Japan

A influência da nicotina na densidade de colágeno em cicatrizes cutâneas, em ratos

Effects of cigarette smoking on early medial collateral ligament healing in a mouse model

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