The Effect of Clonidine Therapy on Height and Growth Velocity in Constitutional Growth and Puberty Delay

Abstract

Background: Constitutional delay of growth and puberty (CDGP) is the most common cause of short stature. This variant of normal growth can be associated with psychological stress in some affected individuals. Objectives: We aimed to assess the effects of clonidine on short-term growth rate in children and adolescents with constitutional growth delay. Patients and Methods: In this prospective, randomized clinical trial study, 48 prepubertal constitutionally short boys (6 -12 years