The effect of combined use of resin infiltration with different bioactive calcium phosphate-based approaches on enamel white spot lesions: An in vitro study

Meng, Qingfei; Wang, Yan; He, Jingyu; Chen, Lijuan; Meng, Jian; Lyons, Karl; Mei, May Lei

doi:10.1016/j.jdent.2024.104909

Cited by 3 publications

(1 citation statement)

References 38 publications

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“…The experimental resin group's roughness escalated again after being subjected to pH cycling difficulties, eventually matching the CN group's similarly high level of roughness. This may result from changes in the polymeric chains of the invasive components brought on by encounters in an acidic environment [ 36 ]. However, research indicates that a gentler pH cycling method (involving a pH shift to 5.0 over 50 days) did not markedly change the microhardness of resin-infiltrated lesions following exposure to acid [ 30 , 37 ].…”

Section: Discussionmentioning

confidence: 99%

A Comparative In Vitro Physicochemical Analysis of Resin Infiltrants Doped With Bioactive Glasses

Ahmed,

Khan,

Aljeshi

et al. 2024

Cureus

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Section: Discussionmentioning

confidence: 99%

A Comparative In Vitro Physicochemical Analysis of Resin Infiltrants Doped With Bioactive Glasses

Ahmed,

Khan,

Aljeshi

et al. 2024

Cureus

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Effect of sodium hypochlorite and EDTA pretreatment on the resin infiltration efficacy and acid resistance of enamel white spot lesions: an in vitro study

Ni,

Chen,

et al. 2024

BMC Oral Health

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Background This in vitro study aimed to evaluate the effect of sodium hypochlorite (NaOCl) and ethylene diamine tetraacetic acid (EDTA) as pretreatments on the resin infiltration efficacy and acid resistance of enamel white spot lesions (WSLs). Methods Enamel blocks prepared from the buccal surfaces of sound human premolars were placed in a demineralisation solution for 3 days to establish artificial enamel WSLs. All the blocks with WSLs were randomly divided into four groups ( n = 40 per group): RI (Control): resin infiltration only. N/RI: 5.25% NaOCl pretreatment + resin infiltration; E/RI: 17% EDTA pretreatment + resin infiltration; NE/RI: combined pretreatment of 5.25% NaOCl with 17% EDTA + resin infiltration; Enamel pore exposure was measured by using SEM observation and Image J software in each group after pretreatment prior to resin infiltration ( n = 8 per group). Resin penetration depth and enamel surface microhardness were assessed after resin infiltration ( n = 8 per group for each test) by a confocal laser scanning microscope and a Vickers’ microhardness test respectively. The remaining specimens were subjected 7 days of pH cycling after which surface enamel roughness and microhardness were assessed by an atomic force microscope and a microhardness test respectively. Results Compared to the control group, the enamel surface pore exposure ( p = 0.007), resin penetration depth ( p = 0.011) and enamel surface microhardness ( p < 0.001) were all significantly increased after the pretreatment of 5.25% NaOCl alone or combined with 17% EDTA by one-way ANOVA. After pH cycling, no significant differences were found in enamel surface roughness or microhardness among the four groups ( p = 0.55) by two-way ANOVA. Conclusions Enamel surface pretreatment of 5.25% NaOCl or combined with 17% EDTA improved the efficacy of the resin infiltration of WSLs, but might be useless in enhancing the acid resistance of resin-infiltrated WSLs.

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Antimicrobial, remineralization, and infiltration: advanced strategies for interrupting dental caries

Yang,

Li,

et al. 2024

Medical Review

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Dental caries, driven by plaque biofilm, poses a major oral health challenge due to imbalance in mineralization and demineralization. The primary objective in caries management is to maintain biofilm homeostasis while facilitating the repair and regeneration of dental hard tissues, thus restoring both structural integrity and functionality of affected teeth. Though antimicrobial and remineralization approaches haven shown promise, their standalone utilization without concurrent bacterial control or rebalancing lacks an integrated strategy to effectively arrest caries progression. Furthermore, according to the principles of minimally invasive dentistry, treatment materials should exhibit high permeability to ensure optimal sealing of demineralized tooth surfaces. The concept of interrupting dental caries (IDC) has emerged as a holistic approach, drawing upon extensive research encompassing three pivotal techniques: antibacterial strategies, remineralization therapies, and infiltration mechanisms, all of which are indispensable components in combating the progression of dental caries. In this review, we provide a comprehensive overview of the mechanisms and applications of antibacterial, remineralization, and infiltration technologies within the context of caries management. Additionally, we summarize advanced materials that align with the IDC concept, aiming to offer valuable insights for designing next-generation materials adept at preventing or halting caries progression efficiently.

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The effect of combined use of resin infiltration with different bioactive calcium phosphate-based approaches on enamel white spot lesions: An in vitro study

Cited by 3 publications

References 38 publications

A Comparative In Vitro Physicochemical Analysis of Resin Infiltrants Doped With Bioactive Glasses

A Comparative In Vitro Physicochemical Analysis of Resin Infiltrants Doped With Bioactive Glasses

Effect of sodium hypochlorite and EDTA pretreatment on the resin infiltration efficacy and acid resistance of enamel white spot lesions: an in vitro study

Antimicrobial, remineralization, and infiltration: advanced strategies for interrupting dental caries

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