The effect of complex treatment on some hematological and hemostasiological indicators during the treatment of generalized periodontitis in patients with different blood group affiliation

Abstract

The article presents the results of treatment of 157 patients with generalized periodontitis depending on blood type. In the blood of patients with generalized periodontitis was determined: the number of erythrocytes, the number of leukocytes, platelets, neutrophils, leukocyte intoxication index, fibrinogen. After treatment, analysis of blood cell composition showed that 1 year after treatment of generalized periodontitis, carriers of 0 (I) and A (II) blood type increased the number of erythrocytes in the blood – 1.2 times. At the same time, a decrease in the number of leukocytes on average was determined by 1.4 times, and leukocyte intoxication index values – by 2.0 times in representatives of 0 (I) and B (III) blood type; neutrophils – 1.4 times in people with A (II) blood type; platelets – 1.3 times in carriers with 0 (I) and AB (IV) blood type, according to data before treatment. The improvement of hematological and hemostasiological indicators of blood in patients with generalized periodontitis indicates a positive effect on the organs and systems the medicines we have prescribed, the positive effect of which is reflected, in particular, on the complex of tooth-retaining tissues.

Submicroscopic changes of periodontal components under experimental periodontitis combined with hypothyroidism

“…The effect of impaired thyroid function on the health of the oral cavity is due to violation of mineral metabolism, redox processes and immunoresistance in such patients. Scientific publications of a number of authors testify to the impact of disruption of thyroid hormone production on the loss of bone tissue, a decrease in its mineral density and the occurrence of osteoporosis [19,20]. Nevertheless, it is difficult to assess this effect in dynamics, since patients with reduced thyroid function are immediately prescribed replacement treatment with the use of hormonal drugs.…”

Features of Changes in Indicators of Local Immunity of the Oral Cavity and Blood Serum of Patients Against the Background of Generalized Periodontitis and Type 2 Diabetes Mellitus

“…It is known that bacteria are constantly present in the oral cavity, which are in direct contact as part of dental plaque with periodontal tissues and are capable of producing a large number of biologically active substances: lipolysaccharide toxin, leukotoxins, collagenases, hydrolytic proteases and others. According to the results of modern scientific research, it has been established that damage to periodontal tissue does not occur directly from the toxicity of bacterial factors, but from the ability of bacterial components to influence the immune response [10,11,12,13]. Therefore, it can be assumed that the development of periodontitis in patients of group 4 is a consequence of hyperactivity and dysregulation of the immune system in type 2 diabetes.…”