The effect of copper on the blood chemistry of Clarias gariepinus (clariidae)

Vuren, J.H.J. van; Merwe, Marinda Van der; Preez, H.H. Du

doi:10.1016/0147-6513(94)90019-1

Cited by 44 publications

(32 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As seen in table1, RBC and WBC counts and hemoglobin content decrease significantly among the miners compared to the control group. Two previous studies on toxic effects of Cu on hematological system of the fish confirmed decrease of RBC count and hemoglobin content due to Cu toxicity, however, increase in WBC counts was reported in both studies (17,18). This finding is in conflict with the results of the present study, which may be due to the different mechanisms of Cu toxicity among humans and fish.…”

Section: Discussioncontrasting

confidence: 57%

Hematological and hepatic alterations among copper mine workers and office employees in a copper mine in the west of Iran, 2015

Lotfi

Rezazadeh

Ebrahimpour

2018

JOHE

View full text Add to dashboard Cite

Article InfoBackground: Workers in different occupational positions experience significant Cu exposures, however, Cu toxicity has not been fully studied as compared to other heavy metals. In the present study, hematological and hepatic alterations have been investigated among copper mine workers. Materials and Methods: This descriptive study was conducted in a copper mine in west of Iran, on 402 copper mine workers (study group) and 52 office employees (control group) during winter 2015. 5ml blood samples were provided from each subject and hematological and hepatic parameters including white blood cell (WBC), platelet (PLT), hemoglobin (HGB), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCH), lymphocytes, neutrophils, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and serum Cu levels have been determined using their commercial kits. The results were analyzed in the SPSS software using t-test and regression method. Results: ALT, AST, HGB, MCV, MCH and plasma Cu levels among the workers were significantly higher than the office employees (p<0.050). WBC and RBC counts among the workers were significantly lower than the control group (p= 0.049 and 0.024, respectively). Serum Cu levels of 215 of the workers were higher than its normal recommended range (120 µg/dl). For the subjects with serum Cu levels above 150 µg/dl, increases in AST and ALT were in compliance with serum Cu levels increase. Conclusions: Significant hepatic and hematological alteration were observed among copper miners compared to control group. Employment of workers with background hematological and hepatic disorders in copper industries must be accompanied with great caution.

show abstract

Section: Discussioncontrasting

confidence: 57%

Hematological and hepatic alterations among copper mine workers and office employees in a copper mine in the west of Iran, 2015

Lotfi

Rezazadeh

Ebrahimpour

2018

JOHE

View full text Add to dashboard Cite

show abstract

“…In addition, bilirubin is a predominant bile pigment found in the circulation in the Nile tilapia derived from disruption of hemoglobin (Folmar, 1993). Serum bilirubin levels of fish could change with hepatocellular disease (Chen et al, 2004) and the effect of mycotoxin (Van Vuren et al, 1994).…”

Section: Discussionmentioning

confidence: 99%

Untitled

Mutlu¹,

Aydin²,

Kutlu³

2015

Turk. J. Fish. Aquat. Sci.

View full text Add to dashboard Cite

The objective of this study was to evaluate the effects of copper sulfate (CuSO 4 , 72 nd and 96 th hours), respectively. The effects of 1.5 mg/L dose of copper sulfate on growth rate, gross clinical observations and blood biochemical parameters of Nile tilapia were evaluated after 35, 65 and 95 days of exposure periods. The differences of growth rates between control and copper sulfate-exposed groups were not significant (P>0.05) at the end of 35, 65 and 95 days. Continuous exposure of Nile tilapia to 1.5 mg/L concentration of copper sulfate in water solution for three periods (35, 65 and 95 days) decreased the total protein, albumin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), glucose (except the elevation in the exposed group at the end of 95 days period), magnesium (Mg + ²), calcium (Ca + ²), iron (Fe + ²), potassium (K + ), sodium (Na +1 ), chloride (Cl -) and phosphate values in serum. The cholesterol, low density lipid (LDL), triglyceride, globulin, creatinine, alkaline phosphatase (ALP), total bilirubin, direct bilirubin, uric acid and blood urea nitrogen (BUN) concentrations in the serum increased in copper sulfate-exposed fish. ), sodyum (Na +1 ), klor (Cl -) ve fosfatın serumdaki değerlerini düşürmüştür. Kolesterol, düşük yoğunluklu lipit (LDL), trigliserit, globülin, kreatinin, alkalin fosfataz (ALP), total bilirubin, direkt bilirubin, ürik asit ve üre azotu (BUN) konsantrasyonları bakır sülfata maruz kalan balıkların serumlarında yükselmiştir. Keywords

show abstract

“…The separated serum was then poured into plastic tubes and stored at -20 °C until use. For sex determination, undamaged fish scales (6)(7)(8) were excised from the lower part of the dorsal fin (above the lateral line) and were analyzed. Serum glucose, cholesterol, and triglycerides were determined by the enzymatic methods; cholesterol oxidase and glycerophosphate dehydrogenase, respectively, and total protein were assessed by the Burette method, for all of which commercial kits (Pars Azmoon, Tehran, Iran) were applied.…”

Section: Methodsmentioning

confidence: 99%

“…Several studies have demonstrated the influence of environmental conditions upon fish blood factors, implying that fish reveal fluctuating blood factors under diverse circumstances (2,3). Different factors including season (4)(5)(6), water contamination (7,8), physicochemical parameters of the water (9,10), stressors (11), age and sex (12,13), and fish species (14) have been shown to affect hematological parameters.…”

Section: Introductionmentioning

confidence: 99%

A comparative study on some blood factors in male and female Caspian kutum (Rutilus frisii kutum) broodstock from southern basin of the Caspian Sea

Firouzbakhsh¹

2013

Turk J Vet Anim Sci

View full text Add to dashboard Cite

The effect of copper on the blood chemistry of Clarias gariepinus (clariidae)

Cited by 44 publications

References 30 publications

Hematological and hepatic alterations among copper mine workers and office employees in a copper mine in the west of Iran, 2015

Hematological and hepatic alterations among copper mine workers and office employees in a copper mine in the west of Iran, 2015

Untitled

A comparative study on some blood factors in male and female Caspian kutum (Rutilus frisii kutum) broodstock from southern basin of the Caspian Sea

Contact Info

Product

Resources

About