The effect of COVID-19 process on patients with endocrinological disease in a pandemic hospital: What happened to the others?

Abstract

Objective: To evaluate the effects of the pandemic process on those with an endocrinological disease that will require close follow-up from the last visit before the pandemic. Materials and methods: Patients of 3,903 with thyroid, calcium-bone metabolism, adrenal gland, pituitary diseases, and neuroendocrine tumor (NET) were retrospectively scanned. The remaining 855 (656 females and 199 males) patients with active disease or who still needed multidisciplinary approaches were included. The number of patients who continued the disease-related medical procedures and could complete these procedures on time in the pandemic period was determined, and medical deprivation rate (MDR) was calculated. Results: The prepandemic period of our patients with thyroid disease (n = 594), calcium-bone metabolism disorder (n = 130), adrenal disease (n = 85), pituitary disease, and NET (n = 46) had MDRs of 85%, 56%, 81%, and 89%, respectively. For each subgroup of patients, the lowest MDR (67%) was in medullary thyroid carcinoma, the highest MDR (89%) was in differentiated thyroid carcinoma; the lowest MDR (6%) was in osteoporosis, the highest MDR (100%) was in the active Paget's disease; the lowest MDR (0%) was in primary adrenocortical insufficiency, the highest MDR (100%) was in hyperfunctional adrenal adenomas; the lowest MDR (81%) was in pituitary nonfunctional adenomas, and the highest MDR (100%) was in Cushing's disease, active prolactinoma, TSHoma, and NET, respectively. Conclusion: This study showed that not only those who had COVID-19 but also those who had medical deprivation due to their current endocrinological disease were not to be underestimated during the pandemic period.

Addison’s Disease: Diagnosis and Management Strategies

“…Of note, a study analyzing medical deprivation rate in patients with endocrine disease during pandemic showed that individuals with AD had the lowest rate (of 0%) as opposed, for instance, with high rates for differentiated thyroid carcinoma (of 89%). 148 …”

“…New data showed that patients with AI did not suffer from new restrictions for a certain period of time as opposed to other endocrine patients and that the first two doses of vaccines required a higher glucocorticoid dose in less than one out of 10 individuals. 148 , 149 …”

“…New data showed that patients with AI did not suffer from new restrictions for a certain period of time as opposed to other endocrine patients and that the first two doses of vaccines required a higher glucocorticoid dose in less than one out of 10 individuals. 148,149 Overall, this review covers a recent, wide area of topics related to AD. As limits of the current work, we acknowledge that we followed a limited timeframe and only using PubMed as literature search might bring a potential bias.…”