The effect of Cu2+ on the interaction between an antitumor drug–mitoxantrone and human serum albumin

Tian, Mingyue; Zhang, Xiufeng; Xie, Le; Xiang, Junfeng; Tang, Yalin; Zhao, Changqi

doi:10.1016/j.molstruc.2008.04.049

Search citation statements

Order By: Relevance

Paper Sections

Select...

Introduction2

Energy Transfer From Bsa To Compound1

Effects Of Common Ions On the Binding Constants Of Eda-bsa C1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2011

2018

Publication Types

Select...

Article10

Relationship

Self Cite0

Independent10

Authors

Journals

Cited by 46 publications

(14 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The binding distance is shorter than 7 nm which indicates that the energy could transfer from BSA to NMQ [52].…”

Section: Energy Transfer From Bsa To Compoundmentioning

confidence: 99%

Synthesis, anticonvulsant, antioxidant and binding interaction of novel N-substituted methylquinazoline-2,4(1H,3H)-dione derivatives to bovine serum albumin: A structure–activity relationship study

Prashanth

Madaiah

Revanasiddappa

et al. 2013

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

View full text Add to dashboard Cite

“…The binding distance is shorter than 7 nm which indicates that the energy could transfer from BSA to NMQ [52].…”

Section: Energy Transfer From Bsa To Compoundmentioning

confidence: 99%

Synthesis, anticonvulsant, antioxidant and binding interaction of novel N-substituted methylquinazoline-2,4(1H,3H)-dione derivatives to bovine serum albumin: A structure–activity relationship study

Prashanth

Madaiah

Revanasiddappa

et al. 2013

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

View full text Add to dashboard Cite

“…These ions participate in many biochemical processes and can affect the reactions between drugs and the serum albumins [24]. The effects of some common metal ions (Mg 2 þ , Ca 2 þ , Cu 2 þ , and Ni 2 þ ) on the binding were investigated at 307 K. The results of Eq.…”

Section: Effects Of Common Ions On the Binding Constants Of Eda-bsa Cmentioning

confidence: 99%

The investigation of the interaction between edaravone and bovine serum albumin by spectroscopic approaches

Yu¹,

Liu²,

Huang³

et al. 2011

Journal of Luminescence

View full text Add to dashboard Cite

a b s t r a c tThe fluorescence and ultraviolet spectroscopies were explored to study the interaction between edaravone (EDA) and bovine serum albumin (BSA) under imitated physiological condition. The experimental results show that the fluorescence quenching mechanism between EDA and BSA is a combined quenching (dynamic and static quenching). The binding constants, binding sites, and the corresponding thermodynamic parameters (DG, DH, and DS) of the interaction system were calculated at different temperatures. According to Förster non-radiation energy transfer theory, the binding distance between EDA and BSA was calculated to be 3.10 nm. The effect of EDA on the conformation of BSA was analyzed using synchronous fluorescence spectroscopy. In addition, the effects of some common metal ions Mg 2 þ , Ca 2 þ , Cu 2 þ , and Ni 2 þ on the binding constant between EDA and BSA were examined.

show abstract

“…Study of the interaction between metal-based drugs and plasma proteins becomes an important research field in chemical biology and pharmacology [1]. Human serum albumin (HSA) is the most abundant protein in plasma.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, structure, protein binding of Cu(II) complexes with a tridentate NNO Schiff-base ligand

Huang

Cheng

et al. 2015

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

View full text Add to dashboard Cite

The effect of Cu2+ on the interaction between an antitumor drug–mitoxantrone and human serum albumin

Cited by 46 publications

References 17 publications

Synthesis, anticonvulsant, antioxidant and binding interaction of novel N-substituted methylquinazoline-2,4(1H,3H)-dione derivatives to bovine serum albumin: A structure–activity relationship study

Synthesis, anticonvulsant, antioxidant and binding interaction of novel N-substituted methylquinazoline-2,4(1H,3H)-dione derivatives to bovine serum albumin: A structure–activity relationship study

The investigation of the interaction between edaravone and bovine serum albumin by spectroscopic approaches

Synthesis, structure, protein binding of Cu(II) complexes with a tridentate NNO Schiff-base ligand

Contact Info

Product

Resources

About