The effect of diabetes on the tensile bond strength of a restorative dental composite to dentin

Saghiri, Mohammad Ali; Freag, Peter; Nath, Devyani; Morgano, Steven M.

doi:10.1007/s10266-022-00697-6

Cited by 3 publications

(5 citation statements)

References 40 publications

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“…Antibacterial activity was also observed against diabetic saliva microcosm. The diabetic saliva microcosm differs from normal saliva, as it has higher numbers of culturable acidogenic bacteria such as streptococci and lactobacilli [5,7]. The composites with Mg-doped ZnO also showed enhanced antibacterial activity against diabetic saliva microcosm at all concentrations.…”

Section: Discussionmentioning

confidence: 98%

“…According to CARS criteria, the control group (two out of three) scored 4, i.e., formation of marginal caries around restoration with underlying dark shadows, hence showing successful caries formation in the rats. Carious defects were formed within the short period due to inoculated biofilm-making bacteria, i.e., S. mutans and E. faecalis, and the caries favorable oral environment was created due to diabetes induction [5][6][7][8]. The composites with Mg-doped ZnO NPs showed intact surfaces, whereas composites with simple ZnO NPs exhibited a score of 2, which is a distinct visual change around the composite.…”

Section: Discussionmentioning

confidence: 99%

“…Due to low pH, salivary flow reduces, causing a low acid buffering effect. Oral microflora shifts towards anaerobic biofilm-making bacteria [5][6][7]. It is also known that diabetics exhibit higher levels of oral anaerobic bacteria compared to those without diabetes [7,8].…”

Section: Introductionmentioning

confidence: 99%

“…Oral microflora shifts towards anaerobic biofilm-making bacteria [5][6][7]. It is also known that diabetics exhibit higher levels of oral anaerobic bacteria compared to those without diabetes [7,8]. Apart from patient characteristics, restoration characteristics are also responsible for SC [8].…”

Section: Introductionmentioning

confidence: 99%

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Dental Composites with Magnesium Doped Zinc Oxide Nanoparticles Prevent Secondary Caries in the Alloxan-Induced Diabetic Model

Tanweer

Rana

Saleem

et al. 2022

IJMS

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Antibacterial restorative materials against caries-causing bacteria are highly preferred among high-risk patients, such as the elderly, and patients with metabolic diseases such as diabetes. This study aimed to enhance the antibacterial potential of resin composite with Magnesium-doped Zinc oxide (Mg-doped ZnO) nanoparticles (NPs) and to look for their effectiveness in the alloxan-induced diabetic model. Hexagonal Mg-doped ZnO NPs (22.3 nm diameter) were synthesized by co-precipitation method and characterized through ultraviolet-visible (UV-Vis), Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS) analysis. The Mg-doped ZnO NPs (1, 2.5 and 5% w/w) were then evaluated for antibacterial activity using a closed system in vitro biofilm model. Significant enhancement in the antibacterial properties was observed in composites with 1% Mg-doped ZnO compared to composites with bare ZnO reinforced NPs (Streptococcus mutans, p = 0.0005; Enterococcus faecalis, p = 0.0074, Saliva microcosm, p < 0.0001; Diabetic Saliva microcosm, p < 0.0001). At 1–2.5% Mg-doped ZnO NPs concentration, compressive strength and biocompatibility of composites were not affected. The pH buffering effect was also achieved at these concentrations, hence not allowing optimal conditions for the anaerobic bacteria to grow. Furthermore, composites with Mg-doped ZnO prevented secondary caries formation in the secondary caries model of alloxan-induced diabetes. Therefore, Mg-doped ZnO NPs are highly recommended as an antibacterial agent for resin composites to avoid biofilm and subsequent secondary caries formation in high-risk patients.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Dental Composites with Magnesium Doped Zinc Oxide Nanoparticles Prevent Secondary Caries in the Alloxan-Induced Diabetic Model

Tanweer

Rana

Saleem

et al. 2022

IJMS

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“…The findings additionally demonstrated that type 1 diabetes mellitus exerted a more pronounced detrimental effect on bond strength compared to type 2 diabetes. The prior work employed a 37% concentration of phosphoric acid to etch dentin specimens uniformly ( 49 ).…”

Section: Discussionmentioning

confidence: 99%

Influence of Diabetes Mellitus and Universal Adhesive Application Mode on the Bond Strength of Composite Resin to Dentine

Attia,

El-Bahrawy,

Shebl

et al. 2024

J Clin Exp Dent

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Background The aim of the current study was to evaluate the influence of diabetes mellitus and the mode of applying a universal adhesive on the shear bond strength of composite resin to dentin. Material and Methods Forty teeth were extracted from diabetic individuals who had been living with diabetes for a period of 5 to 15 years. These forty teeth were divided into two groups: twenty molars from patients with type 1 diabetes and twenty molars from patients with type 2 diabetes. The remaining twenty sound human molars were collected from non-diabetic patients. The collected teeth were assigned into 3 groups, and each group was further divided into 2 subgroups. Group A (n = 20): non-diabetic (ND) where sub group IA: Universal adhesive applied in the total-etch mode (n = 10) and sub group IIA: Universal adhesive applied in the self-etch mode (n = 10). Group B (n = 20): diabetic type 1 (D1) where sub group IB: Universal adhesive applied in the total-etch mode (n = 10) and sub group IIB: Universal adhesive applied in the self-etch mode (n = 10). Group C (n = 20): diabetic type 2 (D2). Where Sub group IC: Universal adhesive applied in the total-etch mode (n = 10) and sub group IIC: Universal adhesive applied in the self-etch mode (n = 10). A Teflon mold measuring 3mm in diameter was attached to the dentin surface, used to build Filtek Z550 to a height of 3mm. The specimens were fixed to the universal testing to measure shear bond strength. Results There was a statistically significant difference of Mean ±SD of shear bond strength among the three tested groups. In group A, the Mean ±SD were (21.710 ± 0.638), it was decreased in group B to (14.626 ± 0.726) and group C to (17.740 ± 0.668). Subgroup I had lower shear bond strength values than subgroup II in all tested groups. The difference between each subgroup in groups A, B, and C was significant. Conclusions 1. Diabetes mellitus has an adverse effect on the shear bond strength of composite to dentine. 2. Type 1 diabetes mellitus significantly reduces the shear bond strength of composite resin to dentin. 3. Shear bond strength of the universal adhesive was higher when applied to dentin using the self-etch mode, as compared to the total etch mode, in all groups, regardless of whether the participants had diabetes or not. Key words: Diabetes Mellitus, Universal Adhesive, Application Mode, Shear bond Strength, Dentine, Composite.

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Mechanical properties of simulated dentin caries treated with metal cations and l-ascorbic acid 2-phosphate

Saghiri,

Vakhnovetsky,

Abdolmaleki

et al. 2023

Odontology

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The effect of diabetes on the tensile bond strength of a restorative dental composite to dentin

Cited by 3 publications

References 40 publications

Dental Composites with Magnesium Doped Zinc Oxide Nanoparticles Prevent Secondary Caries in the Alloxan-Induced Diabetic Model

Dental Composites with Magnesium Doped Zinc Oxide Nanoparticles Prevent Secondary Caries in the Alloxan-Induced Diabetic Model

Influence of Diabetes Mellitus and Universal Adhesive Application Mode on the Bond Strength of Composite Resin to Dentine

Mechanical properties of simulated dentin caries treated with metal cations and l-ascorbic acid 2-phosphate

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