The effect of dichloroacetic acid on the electric and hydrodynamic properties of poly-γ-benzyl-L-glutamate in solution

Ohe, Hidefusa; Yoshioka, Koshiro

doi:10.1007/bf01381691

Cited by 5 publications

(1 citation statement)

References 22 publications

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“…2.1 cm 2 . Taking the molecular weight of the BLG repeating unit as 219.3 g/mol and PBLG density as 1.27 g/cm 3 , , we can then estimate n cp for all VDPRPs using the thickness of the grafted PBLG films. By quantitative analysis of IR spectra of both as-deposited and chemisorbed films (data will be shown later in Figures −), we obtained the ratio of amino acid repeating units of physisorbed to chemisorbed PBLG, which is equal to n pp / n cp ; when multiplied by n cp , it yields n pp .…”

Section: Resultsmentioning

confidence: 99%

Surface-Initiated Vapor Deposition Polymerization of Poly(γ-benzyl-l-glutamate): Optimization and Mechanistic Studies

Zheng

Frank

2009

Langmuir

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Surface-initiated vapor deposition polymerization (SI-VDP) is a very effective approach to synthesize grafted poly(amino acids). In this study, we developed an SI-VDP system with pressure and temperature control and demonstrated highly efficient surface-grafting of poly(γ-benzyl-l-glutamate) (PBLG) on a silicon wafer at pressure 1000 times larger than those in prior reports. More importantly, we developed new methods to quantitatively investigate mechanistic details of the SI-VDP process. First, we monitored the amount of vaporized monomer and developed a VDP reaction profile (VDPRP) method to study the major monomer reservoir processes. Next, we developed a quantitative Fourier transform infrared analysis of both as-deposited PBLG and chemisorbed PBLG films in addition to ellipsometric data to evaluate the major substrate surface processes. We observed two classes of characteristic features (pulses or two peaks) of VDPRPs, which depended upon the monomer temperature, and proposed possible mechanisms. We also found that the two peaks of VDPRPs can selectively track different reservoir processes in real time. For surface processes, we proposed possible mechanisms to obtain the surface-grafted PBLG that are expected to have either high packing density with mostly α-helix segments or low packing density with both random coil and α-helix segments.

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Section: Resultsmentioning

confidence: 99%