The Effect of Different Amounts of Cinnamon Consumption on Blood Glucose in Healthy Adult Individuals

Abstract

Background. This study was aimed at investigating the effect of consumption of different amounts of cinnamon on preprandial blood glucose (PrBG), postprandial blood glucose (PoBG), glycosylated hemoglobin (HbA1c), and body mass index (BMI). Methods. This study was carried out on 41 healthy adult individuals. The individuals were divided into 3 groups and monitored for 40 days. The first, second, and third groups were given 1 g/day, 3 g/day, and 6 g/day cinnamon, respectively. Before the beginning of the consumption of cinnamon, HbA1c and PrBG blood tests of the individuals were examined on an empty stomach at family practice centers. Two hours after these tests were carried out and breakfast, PoBG tests were performed. Results. According to the findings of the study, the differences between the average weight measurements, BMI values, and HbA1c values before consumption on days 20 and 40 were not statistically significant in the individuals consuming 1 g, 3 g, and 6 g of cinnamon a day. The difference between the average PrBG measurements was found to be significant in the individuals consuming 6 g of cinnamon per day. The difference between the average PoBG measurements before consumption on days 20 and 40 was significant in the individuals consuming 1 g, 3 g, and 6 g of cinnamon per day. Conclusions. In particular a 3–6 g of cinnamon consumption was found to affect certain blood parameters of individuals positively. Therefore, it is considered to be beneficial to raise awareness of individuals to be conscious to regularly consume cinnamon.

Effect of Cinnamomum cassia Stem-Bark Extracts on the Synthesis and Secretion of Insulin in RIN-m5F Cells

“…This trend was also observed in these type of extracts when exposed to Type 2 diabetes patients after menopause (Vanschoonbeek et al, 2006). Our results are in accordance with previous study which demonstrated the potential of C. cassia extracts enhance the activity of glycogen synthase, thus, increasing glycogen storage rather than glucose uptake (Kizilaslana and Erden, 2019). Parallel findings reported by Cao et al (2007) have also showed the reduced levels of insulin receptor-β than the absorption of glucose in the mouse 3T3-L1 adipocytes.…”

Traditional Medicine Use among Type 2 Diabetes Patients in KZN

“…e bioactive compounds in tea have the ability to influence signal pathways and key molecules involved in the regulation of insulin, blood sugar, and energy metabolism [79]. On the other hand, the biologically active substances in cinnamon mimic insulin-like properties, including activating insulin kinase, increasing glucose uptake, and autophosphorylating the insulin receptor [80]. A study conducted by Hong et al [81] found that the cinnamon peel extract increases insulin sensitivity and raises glucose intake.…”

Antidiabetic activity of some common medicinal plants

“…Notably, cinnamon's effectiveness in lowering plasma glucose appears most pronounced in individuals with poorly controlled diabetes (Medagama and Bandara, 2014). Studies have indicated that an effective dose consists of 112 mg of aqueous extract taken three times daily, equivalent to a daily intake of 3 grams of Cinnamomum cassia (Kizilaslan and Erdem, 2019). Furthermore, research, including the work of Allen and colleagues, underscores the benefits of cassia cinnamon in reducing fasting plasma glucose levels compared to a placebo.…”