This review provides an overview of the use of pig by-products such as bile salt and their originated bioactive compounds. Pig by-products also increase in production as consumption of meat increases every year, but due to the high cost of processing and the large imbalance in supply and demand over the season, they also change significantly and rely on imported by-products with low price fluctuations. For this reason, a large amount of domestic pork by-products that are not consumed are being discarded. Several studies have conducted to developing the bioactive material such as chenodeoxycholic acid (CDCA) and synthesis of ursodeoxycholic acid (UDCA) from pig by-products. CDCA can be extracted from bile salt in mammals and used as precursors to synthesize UDCA.UDCA is well known as the gallbladder component of bear, and it is used as an improvement in liver function in Korea and the eastern countries. Therefore, gallbladder, which is a by-roduct of pig slaughter, will be available as a material for acquiring bioactive compounds such as UDCA.