The effect of discrete calcium phosphate nanocrystals on bone-bonding to titanium surfaces

Mendes, Vanessa C.; Moineddin, Rahim; Davies, John E.

doi:10.1016/j.biomaterials.2007.07.020

Cited by 197 publications

(220 citation statements)

References 17 publications

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“…In this regard, the traditional surface treatment methods such as grinding, grit blasting, ion implantation, thermal spraying, etc. cannot be employed because they do not help in obtaining a homogeneous surface modification throughout the entire structure [86][87][88][89][90]. Hence, the recent focus was on chemical and/or electrochemical methods because acid-based solution can penetrate through the porous structures through the interconnected pores, producing a homogeneous surface throughout the entire structure [86,[91][92][93].…”

Section: Role Of Post-fabrication Surface Modificationmentioning

confidence: 99%

Advancements in three-dimensional titanium alloy mesh scaffolds fabricated by electron beam melting for biomedical devices: mechanical and biological aspects

Nune

Misra

2017

Sci. China Mater.

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We elucidate here the process-structure-property relationships in three-dimensional (3D) implantable titanium alloy biomaterials processed by electron beam melting (EBM) that is based on the principle of additive manufacturing. The conventional methods for processing of biomedical devices including freeze casting and sintering are limited because of the difficulties in adaptation at the host site and difference in the micro/macrostructure, mechanical, and physical properties with the host tissue. In this regard, EBM has a unique advantage of processing patient-specific complex designs, which can be either obtained from the computed tomography (CT) scan of the defect site or through a computeraided design (CAD) program. This review introduces and summarizes the evolution and underlying reasons that have motivated 3D printing of scaffolds for tissue regeneration. The overview comprises of two parts for obtaining ultimate functionalities. The first part focuses on obtaining the ultimate functionalities in terms of mechanical properties of 3D titanium alloy scaffolds fabricated by EBM with different characteristics based on design, unit cell, processing parameters, scan speed, porosity, and heat treatment. The second part focuses on the advancement of enhancing biological responses of these 3D scaffolds and the influence of surface modification on cell-material interactions. The overview concludes with a discussion on the clinical trials of these 3D porous scaffolds illustrating their potential in meeting the current needs of the biomedical industry.

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Section: Role Of Post-fabrication Surface Modificationmentioning

confidence: 99%

Advancements in three-dimensional titanium alloy mesh scaffolds fabricated by electron beam melting for biomedical devices: mechanical and biological aspects

Nune

Misra

2017

Sci. China Mater.

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“…26,27 Ġmplant yüzey özelliklerinin, osseointegrasyon mekanizmasını destekleyen en önemli faktörlerden biri olduğu kabul edildiğinden, çalıĢmalar osseointegrasyon mekanizmasını optimize etmeye odaklanmıĢ ve implant yüzey modifikasyonları geniĢ oranda incelemiĢtir. 28,29 Günümüzde, dental implantlar titanyum çubuk-ların mekanik olarak iĢlenmesi ve bunu takiben, kumlama 28 , asit 30,31 , veya anodizasyon ile pürüzlendir-me 32,33 , implant yüzeylerinin CaP ile kaplanması 34 , kimyasal modifikasyonlar 28,29,32 gibi iĢlemlerle implant yüzey dizaynının modifiye edilmesi ile üretilir. Üretim tekniklerindeki limitasyonlar nedeniyle açık poröz yapıların oluĢmasını engellenmesine rağ-men, 35,36 porözitenin, por geniĢlikleri ile dağılımlarının ve mekanik özelliklerin kontrol edilebildiği poröz yapıya sahip implantların üretilmesi için talep vardır.…”

Section: öZunclassified

Ki̇şi̇ye Özgü Dental İmplantlar: Derleme

Bağiş¹,

ALTINTOP²,

ADIMCI³

et al. 2016

Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi

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“…The effect of the implant parameters, bone quality and characteristic modulated by different aspects like aging, irradiation, tobaccoism, coffee consumption and alcohol consume, have been evaluated using several laboratory techniques (4,(10)(11)(12). From a macro-biomechanical perspective, the anchorage of implants has been assessed using tensile tests (13), torque (14), pull-out (2) and push-in tests (2). Regarding micromechanical integration, the mechanical properties of surround bone to titanium implants have been evaluated using microindentation (4,15).…”

Section: Introductionmentioning

confidence: 99%

Measurement of Elastic Modulus and Vickers Hardness of Surround Bone Implant Using Dynamic Microindentation - Parameters Definition

et al. 2014

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The clinical performance of dental implants is strongly defined by biomechanical principles. The aim of this study was to quantify the Vicker's hardness (VHN) and elastic modulus (E) surround bone to dental implant in different regions, and to discuss the parameters of dynamic microindantion test. Ten cylindrical implants with morse taper interface (Titamax CM, Neodent; 3.5 mm diameter and 7 mm a height) were inserted in rabbit tibia. The mechanical properties were analyzed using microhardness dynamic indenter with 200 mN load and 15 s penetration time. Seven continuous indentations were made distancing 0.08 mm between each other perpendicularly to the implant-bone interface towards the external surface, at the limit of low (Lp) and high implant profile (Hp). Data were analyzed by Student's t-test ( a=0.05) to compare the E and VHN values obtained on both regions. Mean and standard deviation of E (GPa) were: Lp. 16.6 ± 1.7, Hp. 17.0 ± 2.5 and VHN (N/mm 2 ): Lp. 12.6 ± 40.8, Hp. 120.1 ± 43.7. No statistical difference was found between bone mechanical properties of high and low profile of the surround bone to implant, demonstrating that the bone characterization homogeneously is pertinent. Dynamic microindantion method proved to be highly useful in the characterization of the individual peri-implant bone tissue. Measurement of Elastic Modulus a n d V i c k e r s H a r d n e s s o f Surround Bone Implant Using D y n a m i c M i c r o i n d e n t a t i o n -P a r a m e t e r s D e f i n i t i o n

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The effect of discrete calcium phosphate nanocrystals on bone-bonding to titanium surfaces

Cited by 197 publications

References 17 publications

Advancements in three-dimensional titanium alloy mesh scaffolds fabricated by electron beam melting for biomedical devices: mechanical and biological aspects

Advancements in three-dimensional titanium alloy mesh scaffolds fabricated by electron beam melting for biomedical devices: mechanical and biological aspects

Ki̇şi̇ye Özgü Dental İmplantlar: Derleme

Measurement of Elastic Modulus and Vickers Hardness of Surround Bone Implant Using Dynamic Microindentation - Parameters Definition

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