The effect of donor human milk on the length of hospital stay in very low birthweight infants: a systematic review and meta-analysis

Yang, Rui; Chen, Danqi; Deng, Qingqi; Xu, Xin

doi:10.1186/s13006-020-00332-6

Cited by 17 publications

(18 citation statements)

References 53 publications

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“…Silano et al’s meta‐analysis of four RCTs, which comprised 953 subjects, found that donor human milk did not exert a clear protective effect on surgical NEC when it was compared with formula (RR: 0.45, 95% CI: 0.19–1.09) 9 . Yang et al 10 performed a meta‐analysis of 4 RCTs and 8 observational studies, with a total of 3221 subjects. Donor human milk had no impact on the length of hospital stay, compared with preterm formula, but it generally halved the incidence of NEC and the high‐quality RCTs reported an overall reduction of 68% 10 …”

Section: Does It Provide Vlbw Infants With Significant Health Benefits?mentioning

confidence: 99%

“…Yang et al 10 performed a meta‐analysis of 4 RCTs and 8 observational studies, with a total of 3221 subjects. Donor human milk had no impact on the length of hospital stay, compared with preterm formula, but it generally halved the incidence of NEC and the high‐quality RCTs reported an overall reduction of 68% 10 …”

Section: Does It Provide Vlbw Infants With Significant Health Benefits?mentioning

confidence: 99%

“…3 Silano et al's meta-analysis of four RCTs, which comprised 953 subjects, found that donor human milk did not exert a clear protective effect on surgical NEC when it was compared with formula (RR: 0.45, 95% CI: 0.19-1.09). 9 Yang et al 10 performed a meta-analysis of 4…”

Section: Doe S It Provide Vlbw Infants With S I G Nifi C Ant He Alth ...mentioning

confidence: 99%

“…Donor human milk had no impact on the length of hospital stay, compared with preterm formula, but it generally halved the incidence of NEC and the high-quality RCTs reported an overall reduction of 68%. 10 The best way to manage enteral nutrition in infants recovering from uncomplicated NEC, or surgical NEC requiring a bowel resection, is still a matter of debate. However, mother's own milk or donor human milk provide the best enteral nutrition.…”

Section: Picaudmentioning

confidence: 99%

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Review highlights the importance of donor human milk being available for very low birth weight infants

Picaud

2022

Acta Paediatrica

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One of the key roles of neonatal units is to support the growth and development of preterm infants during the critical period between birth and term equivalent age. Nutritional care is an important part in this process, as it is crucial that these vulnerable babies receive sufficient nutrients. Human milk makes a major contribution to this goal. It also has an indirect effect on growth and development, by alleviating the risk of complications due to premature birth. 1 Mother's own milk is the first choice for preterm infants, but some mothers find it difficult to produce and sustain enough milk to meet their infants' needs. A survey of 11 European countries showed that, on average, only 58% of very low birth weight (VLBW) infants received any breast milk at discharge and the rates ranged from 36% to 80%. 2 Donor human milk should be the second choice in such cases, as this provides VLBW infants with essential nutritional and bioactive components. It also minimises their exposure to cows' milk formulas, which have been associated with an increased risk of necrotising enterocolitis (NEC). 3

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Section: Does It Provide Vlbw Infants With Significant Health Benefits?mentioning

confidence: 99%

Section: Does It Provide Vlbw Infants With Significant Health Benefits?mentioning

confidence: 99%

Section: Doe S It Provide Vlbw Infants With S I G Nifi C Ant He Alth ...mentioning

confidence: 99%

Section: Picaudmentioning

confidence: 99%

See 2 more Smart Citations

Review highlights the importance of donor human milk being available for very low birth weight infants

Picaud

2022

Acta Paediatrica

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“…In past decades there has been a resurgence in the establishment of donor milk banks in an effort to provide HM for vulnerable infants [ 285 ]. Donor milk has been shown to have positive effects of infant mortality and morbidity [ 286 ] whilst being economically cost effective [ 287 ]. We have been active in the formulation of best practice in milk banking which varies according to geography and resources [ 288 ] as well as investigating pasteurization methods.…”

Section: Donor Human Milkmentioning

confidence: 99%

25 Years of Research in Human Lactation: From Discovery to Translation

et al. 2021

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Researchers have recently called for human lactation research to be conceptualized as a biological framework where maternal and infant factors impacting human milk, in terms of composition, volume and energy content are studied along with relationships to infant growth, development and health. This approach allows for the development of evidence-based interventions that are more likely to support breastfeeding and lactation in pursuit of global breastfeeding goals. Here we summarize the seminal findings of our research programme using a biological systems approach traversing breast anatomy, milk secretion, physiology of milk removal with respect to breastfeeding and expression, milk composition and infant intake, and infant gastric emptying, culminating in the exploration of relationships with infant growth, development of body composition, and health. This approach has allowed the translation of the findings with respect to education, and clinical practice. It also sets a foundation for improved study design for future investigations in human lactation.

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The impact of donating milk on the health of milk donors and their infants: A systematic review and meta‐analysis protocol

Berg,

Rani,

Colaizy

et al. 2024

JPGN rep.

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ObjectivesBreast milk is the recommended nutritional source for newborns and has been associated with decreased morbidity in low‐birth‐weight and preterm infants. In situations where breast milk is not available, donor breast milk is an alternative. Milk banking is becoming increasingly common worldwide to meet this need. Although the benefits of donor breast milk for the recipient infant are well established, the health impact on the breast milk donor and the infant of the breast milk donor is an area of current research. We aim to synthesize and evaluate the available evidence regarding the impact of donating breast milk on the health, lactation, and well‐being of the breast milk donor, and the health and growth of the infant of the breast milk donor.MethodsWe will search electronic databases, grey literature, and the websites of relevant international organizations. We will include studies that involve lactating women and their infants, healthy or with health conditions, who donate breast milk, without restrictions on study date, language, or study design. If sufficient homogeneity exists between studies, we will complete meta‐analyses. We will evaluate the risk of bias using the Risk of Bias tool or the Cochrane Risk of Bias in Non‐Randomized Studies tool. We will evaluate the overall certainty of the evidence using the Grading of Recommendations Assessment, Development, and Evaluation approach.ConclusionIn this systematic review and meta‐analysis, we will summarize the current literature regarding the effects of human milk donation on human milk donors and their infants.

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The effect of donor human milk on the length of hospital stay in very low birthweight infants: a systematic review and meta-analysis

Cited by 17 publications

References 53 publications

Review highlights the importance of donor human milk being available for very low birth weight infants

Review highlights the importance of donor human milk being available for very low birth weight infants

25 Years of Research in Human Lactation: From Discovery to Translation

The impact of donating milk on the health of milk donors and their infants: A systematic review and meta‐analysis protocol

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