Background: Due to progressive increase in stroke incidence and need for effective therapy, the effectiveness of biofeedback therapy on the hand function and activities of daily living performances in stroke survivors were studied. Patients and Methods: In this randomized control trial study, 24 participants (mean age 54.75 years) were divided randomly in experiment and control groups. Their affected hands were evaluated before and after intervention using Barthel index questionnaire, Ashworth test and goniometry in elbow, wrist and finger. The two groups received current occupational therapy intervention for 3 months, 3 sessions (each session was 45 minutes) in a week. The experimental group also had 15 minute biofeedback therapy in each session. Results: Biofeedback trained group showed more decrease in spasticity, significants increase in range of motion in elbow (P < 0.001), wrist (P < 0.003) and finger (P < 0.001) and significant increase in activities of daily living performances (P < 0.001). Conclusions: Biofeedback in accompanying with routine occupational therapy promised to be more effective in stroke survivors.