The effect of electrostimulation on barbiturate‐induced sleeping times in rats

Abstract

2:073-079, 1982.Female rats, anaesthetized with hexobarbital, regained their righting reflex more rapidly following electrostimulation than sham-treated controls. The extent of the decreased sleeping times in these animals varied according to the frequency (cycles per second) of the electrostimulation applied. The frequency which produced the largest decrease in sleeping time was 10 Hz. Determination of the activity of some microsomal enzymes indicated that the decreased sleeping time was not the result of increased hepatic enzyme activity. Animals which had received prior treatment with naloxone exhibited increased sleeping times following barbiturate administration, but the effects of electrostimulation on the sleeping time at 10 Hz was diminished, while the effect of electrostimulation at high frequency (500 Hz) was enhanced. Although repeated daily administration of hexobarbital progressively decreased sleeping times for all the animals, electrostimulation decreased the sleeping times of the treated rats by a similar percentage of the control animals on each successive day. Electrostimulation at a frequency of 10 Hz produced a significant decrease in serum corticosterone levels, whereas 500 Hz resulted in an increase.

Aspects related to the interconnection between music and the human brain. Scientific discoveries and contemporary challenges

“…In other words, the brain's internal communication system-its language, if you like -is based on frequency." (Capel, Pinnock, Withey et al, 1982) For example, if the brain is induced alpha brain waves (frequency between 8 and 14 Hz) or is in the Alpha state, they will generate a waking but relaxed state of consciousness, of calm and responsive mind, by producing endorphins and serotonin. The technology of synchronization of cerebral hemispheres -Binaural Beats -relies on this brain response; it is applied under the name of Hemi-Sync audio technology by mixing the frequencies of brain waves with music, sounds from nature, verbal guides; the result is Metamusic, used to induce certain brain frequencies to the brain.…”

“…2 (1981), Concerto Grosso No. 2 (1981-1982), Concerto Grosso No. 3 (1985), The Faust Cantata (1983, Concerto for mixed choir (1984)(1985), music for film -Malenkie tragedii [Little Tragedies] (1979), Ekipazh [The Crew] (1979), Skazka stranstviy [The Tale of Travels] (1982), Myortvye dushi [Dead Souls] (1984).…”