The effect of endometrial polyp resection by office hysteroscopy during in vitro fertilization/intracytoplasmic sperm injection treatment cycle on pregnancy rate   a series of 25 cases

Al-Rshoud, Firas; Kilani, Rami; Asali, Fida; Assi, Omar; Ikhlaif, Nedaa; Maaita, Ward

doi:10.4103/jhrs.jhrs_14_21

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…). Likewise, Al-Rshoud et al demonstrated that out of the total of 49 patients diagnosed with PCOS, 15 patients (31%) were con rmed to possess uterine anomalies(17). As well, Saleh et al's study showed that uterine abnormalities were present in nearly one-third (n = 149, 31.4%) of the 409 patients with diagnosed PCOS(p < 0/001) (18).…”

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A survey of the frequency of polycystic ovary morphology in infertile patients with uterine abnormalities

Irani,

Najafi,

Vesali

et al. 2024

Preprint

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Background: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age. Several studies have shown an association between PCOS and mullerian anomalies. The study aims to evaluate the prevalence of polycystic ovary morphology (PCOM) in infertile patients with uterine anomalies (septate and arcuate uterine) who attended the Royan Research Institute in Tehran (Iran) between January 2021 and December 2022. Methods: The current cross-sectional study was conducted on a total of 884 women who were experiencing infertility and referred to our Institute for 3D-hysterosonography. These women were divided into two groups: the first group consisted of 127 infertile women with uterine anomalies, while the second group included 757 infertile women without uterine anomalies. The employed sampling method was convenience and available. The necessary data were acquired from the patients' files. Subsequently, the frequency of polycystic ovary morphology (PCOM) was assessed and compared between the two groups. Result: Of the 884 patients with infertility who were evaluated, a total of 127 women (14.4%) were found to have uterine anomalies (septate and arcuate anomalies), while the remaining 757 women (85.6%) did not exhibit any such abnormalities. In the subgroup of patients with uterine anomalies, 112 women (88.1%) exhibited arcuate uterine, and 15 women (11.9%) presented with septate uterine. Our study demonstrated that the frequency of PCOM in patients with uterine anomalies was 40.9% (52 women) and in those without such anomalies was 14/7% (111 women) (p=0.0001). Conclusion: According to the study's findings, the prevalence of polycystic ovary morphology in women who have uterine anomalies is higher than in women without these anomalies.

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confidence: 95%

A survey of the frequency of polycystic ovary morphology in infertile patients with uterine abnormalities

Irani,

Najafi,

Vesali

et al. 2024

Preprint

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Controlled Ovarian Stimulation

Al-Rshoud

Darwish

2022

Advances in Assisted Reproduction Technologies

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For conception to occur, whether naturally or via assisted reproductive technology (ART), three things are required; a healthy sperm for fertilization, an ovum released from both ovaries (in the fallopian tubes for natural pregnancy or in the laboratory in IVF/ICSI), and a healthy place for the embryo to implant (a healthy receptive endometrial cavity), so any defect in any of the aforementioned pregnancy requirements will affect the achievement of pregnancy in both types; the natural one or that resulting from ART [1]. Ovarian stimulation is used to overcome any ovulatory disorder or in ART to collect as many eggs as possible (10-15 eggs at least) [2] to maximize the chances of pregnancy. Assessment of ovarian reserve is the first and most important step in ovarian stimulation, as this will indicate the proper method and dose needed for ovulation induction. We test for ovarian reserve using Biomarkers (FSH and AMH) and physical markers (antral follicles count(AFC)) by transvaginal ultrasound(TVS). Both AMH and AFC have similar accuracy in assessing ovarian reserve and are both superior to FSH as they have no cyclic variations [3]. This chapter will discuss all aspects of the physiology of the ovulation process and ovarian stimulation.

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Artificial Oocyte Activation

Ebner

2022

Advances in Assisted Reproduction Technologies

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Against all expectations, the presence of a carefully selected normal spermatozoon does not guarantee oocyte activation/fertilization. In contrast, some ICSI cycles will have to face no or low fertilization in several consecutive cycles. Both sperm- and oocyte-derived problems may account for such a dilemma. In case of physiological activation problems, any artificial increase in ooplasmic calcium could rescue the fertilization process. Such approaches are summarized under the term artificial oocyte activation (AOA). AOA can be achieved by modified ICSI techniques, piezoelectrical manipulation, or chemical stimuli. Amongst these approaches, the latter is the currently most accepted one in IVF laboratories around the world and particularly the Ca2+-ionophores ionomycin and calcimycin are the most extensively studied agents. Recently, a ready-to-use ionophore (A23187) has been introduced which is CE-marked and as such will assist in the standardization of AOA techniques. There is growing evidence that for proper indications usage of AOA can be considered quite safe. This conclusion is based on studies on morphokinetics, chromosome segregation, and gene expression. More importantly, available neonatal and neurodevelopmental data are reassuring. However, since artificial oocyte activation rarely results in physiological Ca2+ oscillations and is not beneficial for all patients with a suspected activation deficiency these techniques should not be used without profound indication.

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The effect of endometrial polyp resection by office hysteroscopy during in vitro fertilization/intracytoplasmic sperm injection treatment cycle on pregnancy rate a series of 25 cases

Cited by 3 publications

References 16 publications

A survey of the frequency of polycystic ovary morphology in infertile patients with uterine abnormalities

A survey of the frequency of polycystic ovary morphology in infertile patients with uterine abnormalities

Controlled Ovarian Stimulation

Artificial Oocyte Activation

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