The effect of enhanced recovery program for patients undergoing partial laparoscopic hepatectomy of liver cancer

He, Feng; Lin, Xiao; Xie, Fang; Huang, Yang; Yuan, Ray-Hwang

doi:10.1007/s12094-015-1296-9

Cited by 60 publications

(104 citation statements)

References 40 publications

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“…ERAS can be always improved, all patients undergoing surgery can benefit from this programs . For patients who have liver diseases and require hepatectomy, whether laparoscopic surgery or laparotomy, liver tumor or hepatolithiasis, segmental hepatectomy or hemihepatectomy, ERAS programs can effectively accelerate the perioperative rehabilitation . However, the ERAS programs cannot be successfully implemented without multidisciplinary collaboration, and it is essential to have teamwork from the departments of surgery, anesthesia, nursing, nutrition, rehabilitation, and other departments …”

Section: Discussionmentioning

confidence: 99%

Safety and efficacy of enhanced recovery after surgery (ERAS) programs in patients undergoing hepatectomy: A prospective randomized controlled trial

Chen

Cao

et al. 2018

Clinical Laboratory Analysis

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Section: Discussionmentioning

confidence: 99%

Safety and efficacy of enhanced recovery after surgery (ERAS) programs in patients undergoing hepatectomy: A prospective randomized controlled trial

Chen

Cao

et al. 2018

Clinical Laboratory Analysis

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“…Six studies were RCTs, 22,25,28,29,32,35 16 were case-control studies 2, 18, 21, 23, 24, 27, 31, 33, 36-42 and five prospective studies. 19,20,26,30,34 Eleven studies included both open and laparoscopic surgery in the study, 19-21, 23, 24, 27, 33, 35, 37, 39, 40 ten studies included only open liver surgery patients, 2, 18, 25, 26, 30-32, 34, 41, 42 five studies included only laparoscopic surgery patients, 22,28,29,36,38 whilst one study performed a separate analysis for laparoscopic surgery and open surgery. 21 A detailed characteristic of included studies is shown in Table 1.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

Enhanced Recovery After Surgery (ERAS) Reduces Hospital Costs and Improve Clinical Outcomes in Liver Surgery: a Systematic Review and Meta-Analysis

Noba

Rodgers

Chandler

et al. 2020

Journal of Gastrointestinal Surgery

152

101

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Background Enhanced recovery after surgery (ERAS) protocols are evidence-based, multimodal and patient-centred approach to optimize patient care and experience during their perioperative pathway. It has been shown to be effective in reducing length of hospital stay and improving clinical outcomes. However, evidence on its effective in liver surgery remains weak. The aim of this review is to investigate clinical benefits, cost-effectiveness and compliance to ERAS protocols in liver surgery. Methods A systematic literature search was conducted using CINAHL Plus, EMBASE, MEDLINE, PubMed and Cochrane for randomized control trials (RCTs) and cohort studies published between 2008 and 2019, comparing effect of ERAS protocols and standard care on hospital cost, LOS, complications, readmission, mortality and compliance. Results The search resulted in 6 RCTs and 21 cohort studies of 3739 patients (1777 in ERAS and 1962 in standard care group). LOS was reduced by 2.22 days in ERAS group (MD = −2.22; CI, −2.77 to −1.68; p < 0.00001) compared to the standard care group. Fewer patients in ERAS group experienced complications (RR, 0.71; 95% CI, 0.65-0.77; p = < 0.00001). Hospital cost was significantly lower in the ERAS group (SMD = −0.98; CI, −1.37 to-0.58; p < 0.0001). Conclusion Our review concluded that the introduction of ERAS protocols is safe and feasible in hepatectomies, without increasing mortality and readmission rates, whilst reducing LOS and risk of complications, and with a significant hospital cost savings. Laparoscopic approach may be necessary to reduce complication rates in liver surgery. However, further studies are needed to investigate overall compliance to ERAS protocols and its impact on clinical outcomes.

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“…Many authors have tried to study applications of ERAS protocols on liver surgeries. (13)(14)(15)(16)(17)(18)(19)(20)(21)(22) and showed ERAS protocol has significant benefit over standard protocols however large number studies and quality metaanalysis are still missing. Purpose of this metaanalysis to compare outcomes between ERAS and conventional group.…”

Section: Discussionmentioning

confidence: 99%

Enhanced recovery after surgery (ERAS) protocols is extremely beneficial in liver surgeries – A metaanalysis

Vasavada

Patel

2020

Preprint

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BACKGROUND: Enhanced recovery after surgery (ERAS) programs aim to improve postoperative outcomes.. This metaanalysis aims to evaluate the impact of ERAS programmes on outcomes following liver surgeries. METHODS: EMBASE, MEDLINE, PubMed and the Cochrane Database were searched for studies comparing outcomes in patients undergoing liver surgery utilizing ERAS principles with those patients receiving conventional care. The primary outcome was occurrence of 30 day morbidity and mortality. Secondary outcomes included length of stay , functional recovery ,readmission rates,time to pass flatus,blood loss and hospital costs. RESULTS: Ten articles were included in the metaanalysis. 30 days morbidity and mortality was significantly less in ERAS group.Hospital stay, time to pass flatus, time to complete recovery and hospital costs were also significantly reduced due to ERAS protocols. Blood loss and readmission rates were also significantly less in ERAS group. CONCLUSIONS: The adoption of ERAS protocols significantly reduced morbidity, mortality hospital stay, readmission rates, time to recovery, hospital costs, time to pass flatus, blood loss and readmission rates.

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The effect of enhanced recovery program for patients undergoing partial laparoscopic hepatectomy of liver cancer

Abstract: This study suggests that ERAS is feasible and safe for laparoscopic hepatectomy.

Cited by 60 publications

References 40 publications

Safety and efficacy of enhanced recovery after surgery (ERAS) programs in patients undergoing hepatectomy: A prospective randomized controlled trial

Safety and efficacy of enhanced recovery after surgery (ERAS) programs in patients undergoing hepatectomy: A prospective randomized controlled trial

Enhanced Recovery After Surgery (ERAS) Reduces Hospital Costs and Improve Clinical Outcomes in Liver Surgery: a Systematic Review and Meta-Analysis

Enhanced recovery after surgery (ERAS) protocols is extremely beneficial in liver surgeries – A metaanalysis

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