The effect of ethnicity on the prevalence of diabetes and associated chronic kidney disease

Abstract

Significant disparities exist between the major ethnic groups in both disease prevalence and management. Future studies examining the management of CKD need to take variation by ethnicity into account.

South Asian diabetic macular oedema treated with ranibizumab (ADMOR)—real-life experience

“…3 Ethnicity is known to influence the prevalence of diabetes, albeit in a complex manner, with many overlapping co-factors. 1,[7][8][9][10][11] In the UK, the prevalence of diabetes within a population of South Asian background is higher than the general population. 10,11 Locally, 74.9% of the NHS Bradford City clinical commissioning group Table 2 The effect of treatment on VA for the n = 9 eyes that were naïve to any prior treatment at baseline The effect of treatment on VA and CMT for the n = 42 eyes that had received treatment for diabetic retinopathy or maculopathy (macular laser, pan-retinal photocoagulation, intravitreal Avastin, or Triamcinolone) prior to intravitreal ranibizumab.…”

“…1,[7][8][9][10][11] In the UK, the prevalence of diabetes within a population of South Asian background is higher than the general population. 10,11 Locally, 74.9% of the NHS Bradford City clinical commissioning group Table 2 The effect of treatment on VA for the n = 9 eyes that were naïve to any prior treatment at baseline The effect of treatment on VA and CMT for the n = 42 eyes that had received treatment for diabetic retinopathy or maculopathy (macular laser, pan-retinal photocoagulation, intravitreal Avastin, or Triamcinolone) prior to intravitreal ranibizumab. Table 3 Comparison of age, visual acuity, and CMT data for subjects with poorer baseline VA (o55 letters) and better baseline VA (≥55 letters) and for subjects with thinner (o500 μm) and thicker (≥500 μm) baseline CMT (CCG) population is South Asian, 14 where prevalence of known diabetes is 8.9% compared with 6.7% in similar sized CCGs.…”

“…15 The prevalence of diabetes can be 2.5-5 times more common among South Asians than the general population. 10,11 In addition, DRIVE UK 1 reported that sight-threatening diabetic retinopathy was significantly more prevalent in Afro-Caribbeans (11.5%) and South Asians (10.3%) compared with white Europeans (5.5%). DMO is more prevalent amongst diabetics with an Asian background than Caucasians.…”

“…[7][8][9][10][11] Furthermore, diabetics of South Asian origin are twice as likely to develop DMO as Caucasians. 1 However, the pivotal studies on ranibizumab use in DMO were primarily based on Caucasian populations, resulting in little useful data on South Asians.…”

Metformin in advanced chronic kidney disease: are current guidelines overly restrictive?

“…Dreyer et al performed a cross-sectional study of 34,359 patients with diabetes in three primary care trusts in the UK. 24 They found that the prevalence of people with an eGFR of <45 mL/min was 5.4%. However, this may be an underestimate because the study population contained a significant number of non-white individuals (who have a lower prevalence of CKD stage 3).…”