The effect of exercise and zinc supplement on the hematological parameters in rats

Abstract

This study evaluates the consequences of a session of intensive short-duration exercise and Zn supplementation on different hematological variables. Forty male Wistar rats were divided into four groups (n = 10): the first nonsupplemented, maintained at rest (R); the second nonsupplemented, undergoing exercise (E); the third supplemented with Zn, kept at rest (ZnR); and the fourth supplemented with Zn, undergoing exercise (ZnE). Zinc supplements (200 ppm) were given in drinking water. The exercise consisted of a single session of swimming until exhaustion. At rest, RBC, Hb, and Hto fell (p < 0.05), whereas red cell indices, MCV, and MCH rose (p < 0.05) in +ZnR compared with R; MCHC remained unchanged (ZnR vs R). After exercise, RBC, Hb, and Hto increased significantly in E and in ZnE compared with R and ZnR, respectively. In addition, RBC and Hb were lower (p < 0.01) in ZnE compared with E; however, MCV and MCH were higher (p < 0.05) in the group ZnE vs E. With respect to white blood cells--leukocytes (WBC), lymphocytes (LYMPH), and neutrophils (NEUT)--no significant differences were observed between groups at rest (ZnR vs R). WBC and LYMPH increased significantly in E with respect to the rest situation (E vs R), but this did not happen in supplemented animals (ZnE vs ZnR). Level of pH decreased after exercise both in E and in ZnE, but the fall was lower in the latter. We believe that a single session of swimming until exhaustion leads to an increase in RBC, Hb, and Hto without causing changes in MCV, MCH, and MCHC.(ABSTRACT TRUNCATED AT 250 WORDS)

Contrasting response of haematological variables between long-term training and short exercise bouts in zebra finches (Taeniopygia guttata)

“…Taken together, we infer a similar response of haematological variables to regular daily training in all endotherms studied in this respect. The response to short-term exercise in zebra finches also resembles that reported for mammals (Cordova et al, 1993;Connes et al, 2006;Zobba et al, 2011), i.e. mammals likewise showed elevated Hct and Hb content immediately after exercise compared with that of individuals at rest.…”

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“…Some studies confirmed the results and they reported increase of Hb and HCT following consumption of zinc supplements in rats swimming in the pool. [13,27] In the present study, the amount of MCH, MCV, and MCHC was not significantly changed after injecting zinc supplements in comparison with the animals receiving no zinc. Besides, a significant change in the number of WBCs following performing physical activity was not observed.…”

“…[8] Moreover, the number of leukocytes and thrombocytes in both groups receiving zinc supplement was not significantly changed compared to the other groups. Similarly, Cordova et al [13] and Baltaci et al [27] also reported that using zinc supplement cannot affect the number of leukocytes after physical activities. In contrast to our results, Kilic et al [28] and Polat [29] found that physical activity can increase the number of leukocytes.…”

“…Cordova et al represented that zinc supplements increased hematological parameters in rats. [13] Southern and Baker reported decrease of hematological parameters, while Donmez et al observed no significant change in hematological parameters following zinc supplements administration. [14] There are limited and sometimes controversial findings on the effects of zinc supplements on hematological parameters after aerobic activities.…”

O sistema imunológico (II): importância dos imunomoduladores na recuperação do desportista

“…Nesse sentido, temos observado em atletas de elite que o treinamento diário de alto nível, ao longo da temporada de competição, provoca importantes modificações no sistema imunológico, tanto em condições basais quanto após o exercício máximo. As alterações imunológicas observadas nos atletas parecem estar associadas com reduções da resistência física e do desempenho 24,25,36,44,45 .…”