Understanding the satisfaction impact factors of China-Eurasia Expo is important to hold and improve the Expo. This paper divides the impact factors of satisfaction into local residents and exhibitors’ aspects. Firstly, this paper constructs a five-dimension conceptual model to measure the local residents’ satisfaction which consists of the degree of promoting economic development, environmental protection, cultural quality, urban convenience and urban brand image of the China-Eurasia Expo. 898 valid questionnaires were collected and structural equation model (SEM) was used to validate the constructed model and the proposed hypotheses were proved; the path coefficients of cultural quality, urban convenience and urban brand image to locals’ satisfaction are all greater than 0.90, indicating that they have high impacts on local residents’ satisfaction, while the path coefficient of the degree of promoting economic development to residents’ satisfaction is 0.695, indicating a relatively low impact. Secondly, this paper constructs a five-dimension conceptual model of exhibitors’ satisfaction which includes infrastructure, management level, service quality, organizing effect, and advancement. 708 valid questionnaires were collected and SEM was used to valid the constructed model and the proposed hypotheses. The results show that the five path coefficients to exhibitors’ satisfaction are higher than 0.7, all hypotheses were proved.