The effect of food consistency and dehydration on reflex parotid and submandibular salivary secretion in conscious rats

Secretion of IgA by rat parotid and submandibular cells in response to autonomimetic stimulation in vitro

“…Our own immunohistochemical studies do not support a large difference in the number of plasma cells between the two glands (results not shown), thus the greater extracellular IgA in the parotid may reflect a lesser IgA secretion (during normal reflex secretion) compared to the submandibular gland. Differences exist between the two glands during normal reflex secretion as submandibular secretion is provoked by chewing, taste and grooming whereas parotid secretion seems to occur mainly in response to chewing and taste [22].…”

Pilocarpine-induced Salivation and Thirst in Conscious Rats

“…A 24-gauge stainless-steel guide cannula for intracerebroventricular injection of drugs was implanted into each rat under sodium pentobarbital anesthesia (60 mg/kg, intraperitoneally injected), as described in our previous studies (Ito et al, 2001(Ito et al, , 2002Nakamura et al, 2005). The cannulas were implanted into the lateral cerebral ventricles 0.8 mm caudal to the bregma, 1.4 mm to the right lateral to the midline, and 2.5 mm below the dura mater.…”

The effect of liquid diet on the parotid gland and the protective role of L-carnitine: immunohistochemical and ultrastructural study

“…The moisture content of diet and the dryness of the mouth alter the volume of parotid saliva secreted and parotid saliva plays an important part in mastication and swallowing [18]. Several experimental studies explored liquid diet consumption and found that it has been held responsible for causing degenerative changes and atrophic changes on submandibular glands [18,34].…”

“…Several experimental studies explored liquid diet consumption and found that it has been held responsible for causing degenerative changes and atrophic changes on submandibular glands [18,34]. Diet-induced glandular alterations are known to occur as a result of chewing restriction.…”

“…Diet-induced glandular alterations are known to occur as a result of chewing restriction. Functional stimulation is an important factor in the development, growth and stability of submandibular glands and liquid diet led to glandular atrophy [22], while higher levels of salivary secretion were detected in animals that were fed with solid diet [18]. Investigating the parotid gland changes on liquid diet is thought in need to shed light on.…”