The Effect of Genetic Counseling for Adult Offspring of Patients with Type 2 Diabetes on Attitudes Toward Diabetes and its Heredity: A Randomized Controlled Trial

Nishigaki, Masakazu; Tokunaga-Nakawatase, Yuri; Nishida, Junko; Kishi, Kazuma

doi:10.1007/s10897-013-9680-5

Cited by 15 publications

(15 citation statements)

References 29 publications

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“…Only one study in this review used communication of familial risk of type 2 diabetes directly to relatives as a tool for behavior change [23] and showed significant changes in some of the primary outcomes. Previous research indicates that informing people about their familial risk increases people's feelings of control over their ability to prevent type 2 diabetes [43], and their perception of personal risk [44], suggesting that such interventions are potentially simpler and cheaper, and require further investigation. One study delivered the intervention online by emailing participants tailored lifestyle recommendations (27).…”

Section: Discussionmentioning

confidence: 99%

Interventions for prevention of type 2 diabetes in relatives: A systematic review

Dimova

Mohan

Swanson

et al. 2017

Primary Care Diabetes

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The relatives and partners of people with type 2 diabetes are at increased risk of developing type 2 diabetes. This systematic review examines randomized controlled trials, written in English that tested an intervention, which aimed to modify behaviors known to delay or prevent type 2 diabetes, among the relatives or partners of people with type 2 diabetes. Study quality was assessed using the Cochrane Collaboration's tool for assessing risk of bias. Seven studies met the inclusion criteria. The majority of studies were at low risk of bias. Six studies tested an intervention in first-degree relatives of people with type 2 diabetes and one in partners. Intervention components and intervention intensity across studies varied, with those targeting diet and physical activity reporting the most significant changes in primary outcomes. Only one study did not observe significant changes in primary outcomes. There were three main recruitment approaches: advertising in the community, recruiting people through their relatives with diabetes, or identifying people as high risk by screening of their own health care contacts. Some evidence was found for potentially successful interventions to prevent type 2 diabetes among the relatives and partners of people with type 2 diabetes, although finding simple and effective methods to identify and recruit them remains a challenge. Future studies should explore the effect of patients' perceptions on their family members' behavior and capitalize on family relationships in order to increase intervention effectiveness.

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Section: Discussionmentioning

confidence: 99%

Interventions for prevention of type 2 diabetes in relatives: A systematic review

Dimova

Mohan

Swanson

et al. 2017

Primary Care Diabetes

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“…The effect of psychological reactions is related to information received and subjective perceptions about a person's risk of disease (Godino et al, 2016). This proves that the counseling process could resolve psychosocial problems for sufferers of diabetes through discussion methods and problem orientation (Eijzenga et al, 2014;Montgomery et al, 2013;Nishigaki et al, 2014). Another statement reveals that genetic counseling can be used as a motivational enhancement approach and emotional support in diabetics (Nishigaki et al, 2014).…”

Section: Depressionmentioning

confidence: 93%

The effect of genetic counseling on depression, anxiety, and knowledge level among diabetes mellitus patients

Setiawan¹,

Sandi²,

Andarini³

et al. 2021

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Aim: The aim of the research was to demonstrate the effect of genetic counseling on depression, anxiety and knowledge level among diabetes mellitus patients. Design: Quasi-experimental study. Methods: A quantitative study that used a questionnaire instrument to assess participants' levels of depression, anxiety, and knowledge. A total of 38 diabetes mellitus patients who met the inclusion criteria were studied for two months at the Lakbok Public Health Center with genetic counseling. Outcomes were measured before and after the counseling intervention provided. The statistical analysis was performed using the IBM SPSS version 25.0 software. Results: The results showed that the majority of participants (76.3%) had moderate depression prior to the genetic counseling intervention. However, after the intervention, most of the participants (73.7%) experienced mild depression, with a change in mean ± standard deviation (SD) pre-post 26.3 ± 3.1 to 17.6 ± 2.6. The anxiety level of most participants was moderate (73.7%). After the intervention, most participants experienced mild anxiety (86.8%) with a change in mean ± SD 16.7 ± 3.3 to 11.3 ± 2.3. In addition, before the intervention the knowledge level of the majority of the participants was satisfactory (86.8%). After the intervention, the knowledge level of the majority of the participants became good (52.6%) with a change in the mean ± SD of 12.8 ± 1.4 to 16.1 ± 2.3. Conclusions: Changes in the level of depression, anxiety and knowledge in different categories are real evidence of the consistency of the intervention's effect on these very significant factors that have implications for health services in various health facilities such as hospitals and public health centers. Therefore, serious efforts are needed so that health policies encourage the presence of genetic counseling services for DM patients and patients of other genetic diseases.

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“…Recently, individuals’ genotypes have been shown to be associated with variable responses to lifestyle interventions in individuals with prediabetes and women at risk of GDM. In the USA and Japan, researchers examined whether genetic counseling for individuals at risk of having diabetes would motivate behavioral change, but failed to show significant improvement, at least in the short term. Prospective analysis of the Diabetes Prevention Study also showed that intensive lifestyle modification was effective regardless of genetic risk, and was effective even in individuals with the highest genetic risk.…”

Section: Using Genomic Markers To Guide Diabetes Prevention and Treatmentioning

confidence: 99%

Precision medicine in diabetes prevention, classification and management

Xie

Chan

2018

J of Diabetes Invest

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Diabetes has become a major burden of healthcare expenditure. Diabetes management following a uniform treatment algorithm is often associated with progressive treatment failure and development of diabetic complications. Recent advances in our understanding of the genomic architecture of diabetes and its complications have provided the framework for development of precision medicine to personalize diabetes prevention and management. In the present review, we summarized recent advances in the understanding of the genetic basis of diabetes and its complications. From a clinician's perspective, we attempted to provide a balanced perspective on the utility of genomic medicine in the field of diabetes. Using genetic information to guide management of monogenic forms of diabetes represents the best‐known examples of genomic medicine for diabetes. Although major strides have been made in genetic research for diabetes, its complications and pharmacogenetics, ongoing efforts are required to translate these findings into practice by incorporating genetic information into a risk prediction model for prioritization of treatment strategies, as well as using multi‐omic analyses to discover novel drug targets with companion diagnostics. Further research is also required to ensure the appropriate use of this information to empower individuals and healthcare professionals to make personalized decisions for achieving the optimal outcome.

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The Effect of Genetic Counseling for Adult Offspring of Patients with Type 2 Diabetes on Attitudes Toward Diabetes and its Heredity: A Randomized Controlled Trial

Cited by 15 publications

References 29 publications

Interventions for prevention of type 2 diabetes in relatives: A systematic review

Interventions for prevention of type 2 diabetes in relatives: A systematic review

The effect of genetic counseling on depression, anxiety, and knowledge level among diabetes mellitus patients

Precision medicine in diabetes prevention, classification and management

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