The effect of gibberellic acid (GA3) on some phenolic substances in globe artichoke (Cynara cardunculus var. scolymus (L.) Fiori)

Sharafeldin, M. A.; Schnitzler, W. H.; Nitz, G.; Razin, A. M.; El-Oksh, I. I.

doi:10.1016/j.scienta.2006.12.002

Cited by 24 publications

(16 citation statements)

References 7 publications

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“…It has also been earlier shown that application of exogenously applied phytohormones influences the physiological and metabolic processes in many plant organ and cell cultures. Previous reports have demonstrated changes in metabolism and accumulation of anthocyanins, flavonoids, etc., on application of GA 3 (39,40).…”

Section: Tissue-specific Transcript Profile-wsosc/bs Wsosc/ls and Wmentioning

confidence: 99%

Cloning and Functional Characterization of Three Branch Point Oxidosqualene Cyclases from Withania somnifera (L.) Dunal

Dhar

Rana

Razdan

et al. 2014

Journal of Biological Chemistry

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Background: Pharmacological investigations position withanolides as important bioactive molecules demanding their copious production. Results: Differential transcriptional and translational expression of three oxidosqualene cyclases leads to redirection of metabolic fluxes. Conclusion: Negative regulator channelizes substrate pool toward cycloartenol synthase at subdividing junction leading to enhanced withanolide production. Significance: Understanding the regulatory role of oxidosqualene cyclases on withanolide accumulation could serve as a prognostic tool for metabolic engineering.

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Section: Tissue-specific Transcript Profile-wsosc/bs Wsosc/ls and Wmentioning

confidence: 99%

Cloning and Functional Characterization of Three Branch Point Oxidosqualene Cyclases from Withania somnifera (L.) Dunal

Dhar

Rana

Razdan

et al. 2014

Journal of Biological Chemistry

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“…In addition, they observed a significant planting density ¥ head parts interaction, particularly in the inner bracts, where the TPC increased 108% from the lower to the higher plant density. Sharaf-Eldin et al (2007) studied the possible interaction between gibberellic acid, supplied to the plants during the crop cycle used to shorten time to harvest for globe artichoke field plants, and the content of 2 phenolic acids (chlorogenic acid and 1,5-Odicafeoylquinic acid) in leaves and receptacle of globe artichoke both grown from field transplants and by direct field seeding. They observed an increase of chlorogenic acid in leaves of globe artichoke grown from field transplants, while no significant differences were found for 1,5-Odicafeoylquinic acid, as well for the receptacle in both types of field trials.…”

Section: Crop Management Factorsmentioning

confidence: 99%

Polyphenol Profile and Content in Wild and Cultivated Cynara Cardunculus L.

Pandino

Lombardo

Williamson

et al. 2012

Italian Journal of Agronomy

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The species Cynara cardunculus L. is native to the Mediterranean Basin, where its commercial production makes a significant contribution to the agricultural economy. It contains phenolic acids and flavones, which play an important role in diet, because of their beneficial effects on human health, and in industrial processing, due to the browning phenomenon. The quantitative and qualitative profile of these compounds is affected by different factors, such as genotype, environmental conditions, crop management and processing procedures. As a consequence, these are relevant for defining the quality of the product. Therefore, our aim was to review the main factors that influence polyphenol biosynthesis and degradation in C. cardunculus. From available data in literature, the genetic background appears to be the main factor, followed by environmental effects. However, crop management also could be a valuable tool to enhance the polyphenol content. C. cardunculus also provides substantial quantities of polyphenol-rich by-products, which could be considered as a natural source of health-promoting compounds and an added value for the farming business

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“…ALE, particularly the one produced from the Cynara scolymus cultivar, has been identified as a potent phytotherapic agent for several comorbidities, including cardiovascular, hepatic and gastric diseases [7]. Phenolic compounds such as cynarin, luteolin and chlorogenic acid, in conjunction with the soluble fibres inulin and pectin, are the main substances believed to be involved with the mechanisms of action attributed to artichoke [13,14].…”

Section: Introductionmentioning

confidence: 99%

The effect of artichoke on lipid profile: A review of possible mechanisms of action

Santos

Bueno

Mota

2018

Pharmacological Research

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Cardiovascular disease is a highly prevalent issue worldwide, and one of its main manifestations, dyslipidaemia, needs more attention. Cooked artichoke (Cynara scolymus) hearts or artichoke leaf extract (ALE) are believed to be helpful in the treatment of dyslipidaemia. In this narrative review, we provide a brief overview of the potential impact of artichoke consumption on lipid profile. We appraised the Cochrane, MEDLINE and Web of Science databases, and included articles published between 2000 and June 2018 on intervention in humans only. The main potential of ALE administration observed on lipid profile relates to decreased serum LDL, total cholesterol and triglyceride concentrations, although no strong evidence for increasing HDL appears to exist. Evidence suggests that decreases of 8-49 mg/dL for LDL concentration, 12-55 mg/dL for total cholesterol, and 11-51 mg/dL for triglycerides, can be attributed to 2 to 3 g/d of ALE, in which its components luteolin and chlorogenic acid may play a key role. On the other hand, the effects of cooked artichoke hearts can be attributed mainly to its soluble fibres, particularly inulin. Despite the convincing evidence on its health benefits, additional long-term clinical trials are pivotal to fully elucidate the potential effects of ALE administration on positive cardiovascular outcomes.

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The effect of gibberellic acid (GA3) on some phenolic substances in globe artichoke (Cynara cardunculus var. scolymus (L.) Fiori)

Cited by 24 publications

References 7 publications

Cloning and Functional Characterization of Three Branch Point Oxidosqualene Cyclases from Withania somnifera (L.) Dunal

Cloning and Functional Characterization of Three Branch Point Oxidosqualene Cyclases from Withania somnifera (L.) Dunal

Polyphenol Profile and Content in Wild and Cultivated Cynara Cardunculus L.

The effect of artichoke on lipid profile: A review of possible mechanisms of action

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