The effect of graphene loading on mechanical, thermal and biological properties of poly(vinyl alcohol)/graphene nanocomposites

Surudžić, Rade D.; Janković, Ana; Mitrić, Miodrag; Matić, Ivana Z.; Juranić, Zorica D.; Živković, Ljiljana; Mišković‐Stanković, Vesna; Rhee, Kyong-Yop; Park, Soo‐Jin; Hui, David

doi:10.1016/j.jiec.2015.11.016

Cited by 64 publications

(42 citation statements)

References 45 publications

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“…2(a)), and it can significantly improve the mechanical properties, thermal stability and gas barrier ability of polymers and reduce its flammability as well [10,[39][40][41]. As shown in Fig.…”

Section: Graphene and Graphene Oxide Flame Retardantsmentioning

confidence: 98%

Graphene-based flame retardants: a review

Sang

et al. 2016

J Mater Sci

191

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Graphene and its derivatives are potential flame retardant materials with good flame retardant performance; in particular, graphene as an adjuvant in combination with inorganic nanomaterials may be a promising candidate of flame retardant. This review describes the flame retardant mechanism, the development trend, and the classification of graphene-based flame retardants. It points out that graphene has attracted intensive interests in the fields of electronics, energy, and information, due to its excellent properties such as high thermal conductivity, good electron transport ability, and large specific surface area. In the meantime, graphene can change the pyrolysis as well as the thermal conductivity, heat absorption, viscosity and dripping of polymer during the combustion process. In other words, graphene can improve the thermal stability of polymer and delay its ignition, and it can also inhibit fire from spreading and reduce heat release rate.

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Section: Graphene and Graphene Oxide Flame Retardantsmentioning

confidence: 98%

Graphene-based flame retardants: a review

Sang

et al. 2016

J Mater Sci

191

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“…All these properties could provide reinforcement to the polymeric materials, so graphene is often included in a polymer matrix as a nano-fi ller. The overall mechanical properties of the hydrogel matrices were shown to be improved by even small amounts of graphene in PVA/Gr hydrogels [33][34][35]. There is also a recent interest in the potential antibacterial activity of graphene [36], which could be benefi cial for wound dressing or soft tissue implant applications, as these properties could provide additional bactericidal effects together with AgNPs, especially in the early phases of application to prevent biofi lm formation.…”

Section: Introductionmentioning

confidence: 99%

In Vivo Investigation of Soft Tissue Response of Novel Silver/Poly(Vinyl Alcohol)/ Graphene and Silver/Poly(Vinyl Alcohol)/Chitosan/Graphene Hydrogels Aimed for Medical Applications – The First Experience

et al. 2018

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In this paper, we have shown for the fi rst time the soft tissue response of novel silver/ poly(vinyl alcohol)/graphene (Ag/PVA/Gr) and silver/poly(vinyl alcohol)/chitosan/ graphene (Ag/PVA/CHI/Gr) nanocomposite hydrogels aimed for medical applications. These novel hydrogels were produced by in situ electrochemical synthesis of silver nanoparticles in the polymer matrices as described in our previously published works. Both Ag/PVA/Gr and Ag/PVA/CHI/Gr, as well as controls Ag/PVA, Ag/PVA/CHI and commercial Suprasorb©hydrogel discs, were implanted in the subcutaneous tissue of rats. Implants with the surrounding tissue were dissected after post-implantation on days 7, 15, 30 and 60, and then processed for histological examination. The tissue irritation index (TIrI) score, according to ISO 10993-6, 2007, as well as the number of leukocytes in the peri-implant zone and connective tissue capsule thickness were examined. The results show that each TIrI score, the leukocyte number around the implanted materials and capsule thickness gradually decreased during the observation period. At the endpoint of follow-up, the Ag/PVA/CHI/Gr implant was surrounded with a thinner capsule, while both the TIrI score and the number of leukocytes of the peri-implant zone were greater compared to the Ag/PVA/Gr implant. Despite the observed differences, we can conclude that our in vivo experiment suggested that both novel hydrogels were biocompatible and suitable for medical use.

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“…tensile strength, thermal stability and conductivity. [21,22] By incorporating graphene into the PVA polymer matrix, we attempted to improve specific properties of Ag/PVA/Gr nanocomposite hydrogels with respect to their topical application. The wound dressings for severe wounds are aimed for prolonged use, over the course of several weeks, during which the dressing is supposed to retain most of its mechanical strength, elasticity, exudate absorption ability and antibacterial activity.…”

Section: Introductionmentioning

confidence: 99%

“…[23] This was also confirmed for PVA/Gr and Ag/PVA/Gr nanocomposites in our previous work. [21,24,25] Additionally, several studies indicated that graphene possesses a certain degree of antibacterial activity, with the ability to induce membrane rupture and oxidative stress of bacterial cells. [26,27] This could be an important property, especially in the initial period of Ag/PVA/Gr wound dressing application, when Gr presence could enhance the antibacterial properties of AgNPs and help prevent wound infection and biofilm formation.…”

Section: Introductionmentioning

confidence: 99%

Graphene Based Composite Hydrogel for Biomedical Applications

Nešović¹,

Abudabbus²,

Rhee³

et al. 2017

Croat. Chem. Acta

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In this work, composite hydrogel consisting of poly(vinyl alcohol), graphene and silver nanoparticles, (Ag/PVA/Gr), was prepared by the immobilization of silver nanoparticles (AgNPs) in PVA/Gr hydrogel matrix in two steps. The first step was cross linking of the PVA/Gr colloid solution by the freezing/thawing method, while in the second step, in situ electrochemical method was used to incorporate AgNPs inside the PVA/Gr hydrogel matrix. We used UV-vis spectroscopy, cyclic voltammetry, Raman spectroscopy, DSC analysis, as well as test of cytotoxicity and antibacterial activity, to characterize obtained Ag/PVA/Gr hydrogel. It was shown that graphene-based composite hydrogel with incorporated AgNPs is non toxic biomaterial with antibacterial activity, with a potential for use in biomedical purposes.

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The effect of graphene loading on mechanical, thermal and biological properties of poly(vinyl alcohol)/graphene nanocomposites

Cited by 64 publications

References 45 publications

Graphene-based flame retardants: a review

Graphene-based flame retardants: a review

In Vivo Investigation of Soft Tissue Response of Novel Silver/Poly(Vinyl Alcohol)/ Graphene and Silver/Poly(Vinyl Alcohol)/Chitosan/Graphene Hydrogels Aimed for Medical Applications – The First Experience

Graphene Based Composite Hydrogel for Biomedical Applications

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