This research aims to explore the potential applications of advanced blockchain technology such as DeFi (decentralized finance) and NFTs (non-fungible tokens) in supporting halal micro, small, and medium enterprises (MSMEs). Through theoretical analysis and case studies, the research identifies how these technologies can be integrated within the framework of Islamic finance, while highlighting the emerging ethical and operational implications. The methodology of this research involves extensive literature review and content analysis of existing blockchain projects. The results show that DeFi and NFTs offer significant opportunities for halal MSMEs in gaining easier access to financing, reducing transaction costs, and increasing the speed and transparency of financial operations.