The effect of heat application on pain, stiffness, physical function and quality of life in patients with knee osteoarthritis

Yıldırım, Nurcan; Ulusoy, Meltem; Bodur, Hatice

doi:10.1111/j.1365-2702.2009.03070.x

Cited by 44 publications

(27 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Heat stimulation was known to relieve the pain in OA patients [29], [30], however, the effect has not been sufficiently investigated in clinical studies and the mechanism remains unknown. The direct effect of heat on metabolism and repair of the articular cartilage, the mainly affected tissue of OA, is also unknown.…”

Section: Introductionmentioning

confidence: 99%

Periodic Heat Shock Accelerated the Chondrogenic Differentiation of Human Mesenchymal Stem Cells in Pellet Culture

Chen

Wang

2014

PLoS ONE

View full text Add to dashboard Cite

Osteoarthritis (OA) is one of diseases that seriously affect elderly people's quality of life. Human mesenchymal stem cells (hMSCs) offer a potential promise for the joint repair in OA patients. However, chondrogenic differentiation from hMSCs in vitro takes a long time (∼6 weeks) and differentiated cells are still not as functionally mature as primary isolated chondrocytes, though chemical stimulations and mechanical loading have been intensively studied to enhance the hMSC differentiation. On the other hand, thermal stimulations of hMSC chondrogenesis have not been well explored. In this study, the direct effects of mild heat shock (HS) on the differentiation of hMSCs into chondrocytes in 3D pellet culture were investigated. Periodic HS at 41°C for 1 hr significantly increased sulfated glycosaminoglycan in 3D pellet culture at Day 10 of chondrogenesis. Immunohistochemical and Western Blot analyses revealed an increased expression of collagen type II and aggrecan in heat-shocked pellets than non heat-shocked pellets on Day 17 of chondrogenesis. In addition, HS also upregulated the expression of collagen type I and X as well as heat shock protein 70 on Day 17 and 24 of differentiation. These results demonstrate that HS accelerated the chondrogenic differentiation of hMSCs and induced an early maturation of chondrocytes differentiated from hMSCs. The results of this study will guide the design of future protocols using thermal treatments to facilitate cartilage regeneration with human mesenchymal stem cells.

show abstract

Section: Introductionmentioning

confidence: 99%

Periodic Heat Shock Accelerated the Chondrogenic Differentiation of Human Mesenchymal Stem Cells in Pellet Culture

Chen

Wang

2014

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…Yıldırım et al. () found hot application to be effective in decreasing the pain and difficulty experienced while performing daily activities but not for stiffness in their study where the effectiveness of superficial local hot application was evaluated. Metin and Hakgüder () report cold application to provide a significant improvement in pain, morning stiffness and activity parameters in the study that investigated the clinical effectiveness of intermittent and continuous cold applications in knee osteoarthritis.…”

Section: Discussionmentioning

confidence: 97%

“…Life quality was evaluated in only a small percentage of these studies (Brosseau et al., ; Denegar et al., , ; Yıldırım et al., ). Yıldırım et al.…”

Section: Discussionmentioning

confidence: 99%

The effect of self‐administered superficial local hot and cold application methods on pain, functional status and quality of life in primary knee osteoarthritis patients

Açıksöz

Akyüz

Tunay

2017

Journal of Clinical Nursing

View full text Add to dashboard Cite

show abstract

“…Yapılan çalışmalarda, diz OA'lı hastalara uygulanan yüzeyel sıcak uygulamanın ağrıyı azalttığı ve fiziksel fonksiyonu arttırdığı saptanmıştır [25,26]. Sıcak uygulama ve egzersizin diz OA yönetiminde etkinliğinin incelendiği bir başka çalışmada ise sıcak uygulama ve egzersizin birlikte uygulanmasının ağrı ve tutukluğu azalttığı, fiziksel fonksiyonu arttırdığı belirlenmiştir [27].…”

Section: Sıcak Uygulamaunclassified

Integrative Health Practices Used in Individuals Diagnosed With Osteoarthritis

Doğan¹,

Göriş²,

Kılıç³

2017

Spatula DD

View full text Add to dashboard Cite

ÖZETOsteoartrit, eklem kıkırdak yapısında bozulma sonucu hareketlerde kısıtlanma ve ağrıya neden olarak bireylerin yaşamını önemli derecede etkileyen kronik bir hastalıktır. Osteoartritin etkin tedavisinde, farmakolojik tedavilerle birlikte bütünleşik sağlık uygulamalarının kullanılması önerilmektedir. Osteoartrite bağlı gelişen ağrı, eklem tutukluğu ve fiziksel fonksiyonlarda azalma gibi sorunların kontrolünde bütünleşik uygulamaların kullanımı giderek artmaktadır. Osteoartritli bireylerde sık kullanılan bütünleşik sağlık uygulamalarının arasında; egzersiz, akupunktur, sıcak uygulama, masaj, yoga ve Tai Chi yer almaktadır. Bu derlemede, osteoartritli bireylerde kullanılan bazı bütünleşik sağlık uygulamalarına, konuyla ilgili yapılmış çalışmalara ve hemşirenin bu konudaki sorumluluklarına yer verilmiştir. ANAHTAR SÖZCÜKLER:Osteoartrit; bütünleşik sağlık uygulamaları; hemşirelik Integrative health practices used in individuals diagnosed with osteoarthritis ABSTRACTOsteoarthritis is a chronic disease and causes deterioration of articular cartilage structure, which seriously affects the lives of individuals with limitation of movement and pain. Along with pharmacological treatments, the use of integrative treatment methods is suggested for effective treatment of osteoarthritis. The use of integrative practices in control of problems associated with osteoarthritis such as pain, joint involvements, and decreased physical functions has been gradually increasing. Integrative treatment methods frequently used in treatment of osteoarthritis include; exercise, acupuncture, hot application, massage, yoga, and tai-chi. In this review, information regarding some integrative practices used in individuals with osteoarthritis and responsibilities of nurses in these practices was given.

show abstract

The effect of heat application on pain, stiffness, physical function and quality of life in patients with knee osteoarthritis

Abstract: The data obtained in this study on the efficiency of heat application on pain, stiffness, physical function and general health perception of patients with knee osteoarthritis may offer an insight into decision-making process for appropriate intervention.

Cited by 44 publications

References 23 publications

Periodic Heat Shock Accelerated the Chondrogenic Differentiation of Human Mesenchymal Stem Cells in Pellet Culture

Periodic Heat Shock Accelerated the Chondrogenic Differentiation of Human Mesenchymal Stem Cells in Pellet Culture

The effect of self‐administered superficial local hot and cold application methods on pain, functional status and quality of life in primary knee osteoarthritis patients

Integrative Health Practices Used in Individuals Diagnosed With Osteoarthritis

Contact Info

Product

Resources

About