The effect of herbal treatment of Hyphaene Thebaica (Doum) and Nelumbo Nucifera (Lotus) on Induced Hyperlipidemia and Hypertension in Male Wistar Albino Rats

Abstract

Hyperlipidemia is a condition in medical terms where any lipid profile or else the lipoproteins are increased in the blood stream. Elevated LDL is risky and the best indicator of atherosclerosis risk. Hypertension is one of the most associated disease with dyslipidemia. For HDL-C, the risk of hypertension is supposed to be increased at such low levels. There are various medicinal plants, which are supposed to be a very important source for upcoming chemical substances which are having the potential for therapeutic effects. There are various phenolic as well as flavonoids substances present in Hyphaene Thebaica (Doum). These ingredients usually work as an antioxidant that are very helpful to provide a control towards hyperlipidemic. Hyphaene Thebaica has antimicrobial, antidiabetic antihypertensive, hypolipidemic and antioxidant effects. Yet another element called as Nelumbo Nucifera (Lotus) is very useful for medicinal purposes in terms of Oriental medicine. These plants are very hypolipidemic, antioxidant activity, antipyretic, antiplatelet activity and hypoglycemic activity.Objective of the study: to estimate the effects of doum and lotus methanolic extracts on hyperlipidemia, hypertension and diabetes on lipid profile parameters and hypertension parameters like angiotensin converting enzyme and aldosterone. Material and Methods:The study in this paper was done on fourth rats with the species of Wistar Albino. These rats are divided in to four groups and all are male samples. First one was control group and hyperlipidemia and hypertension induced in three groups. Feeding hyperlipidemic and hypertensive rats with extract of doum in third group and lotus extract in fourth group. Results:The effect of both extracts on lipid profile parameters, Angiotensin converting enzyme and aldosterone were parallel in significant lowering them. Doum had strong effect on body weight but lotus had strong effect on fasting blood glucose level.

An Overview of Some Medicinal Plants used in Northern Nigeria for the Treatment of Hypertension

“…Also antihypertensive effect of 50 of the 59 medicinal plants reported in this review were previously experimentally verified (Eturk, 2006;Tabassum and Ahmad, 2011;Nsuadi et al, 2013;Shah et al, 2014;Abubakar et al, 2015;Eghianruwa et al, 2016;Jacobs et al, 2020;Kamyab et al, 2020;Obode et al, 2020;Elmahdy et al, 2022;Saeed et al, 2022) (Eturk, 2006;Tabassum and Ahmad, 2011;Nsuadi et al, 2013;Shah et al, 2014;Abubakar et al, 2015;Eghianruwa et al, 2016;Jacobs et al, 2020;Kamyab et al, 2020;Obode et al, 2020;Elmahdy et al, 2022;Saeed et al, 2022). (Eturk, 2006;Tabassum and Ahmad, 2011;Nsuadi et al, 2013;Shah et al, 2014;Abubakar et al, 2015;Eghianruwa et al, 2016;Jacobs et al, 2020;Kamyab et al, 2020;Obode et al, 2020;Elmahdy et al, 2022;Saeed et al, 2022). CONCLUSION This review has successfully documented a wide range of medicinal plants used by the population of Northern Nigeria to treat hypertension, thus preventing the loss of knowledge and providing a basis for pharmacological research.…”

Restoring Antioxidant Levels of Nicotine Injected Rats Using Suggested Dietary Formulas

“…Tahoon, (2021) indicated that cabbage extract increased FER in obese rats as compared to the positive control group. Elmahdy et al, (2022) found that feeding hyperlipidemic and hypertensive rats with an extract of doum increased body weight as compared to the control group. Carob (Ceratonia siliqua L.) pulp powder improved BWG, FI & FER in broiler chicken (Mahmoudi et al, 2022).…”