The effect of hydrogen peroxide (H2O2) on carbon nanotubes solubility as drug delivery material for cancer with covalent functionalization

The Effect of Polyethylene Glycol on the Toxicity Properties of Functionalized Carbon Nanotubes with the Variations of Hydrochloric Acid (HCl)

“…This result is because pure CNT has van der Waals bonds with a robust tensile strength so that the CNT will quickly become bundles. This formation indicates that the appearance of aggregates and tangled tissue on the CNT causes the CNT not to be able to spread appropriately in the solvent (aquades) [12]. This result is following the results of FTIR, which showed that the transmittance intensity obtained by the CP sample was higher among all CPf samples.…”

“…1. That treatment produces the most stable covalent bond, which is almost 50% dissolved in distilled water [12].…”

“…functionalized samples that occur at temperatures lower than the temperature of the mass decrease in pristine indicates the damage that occurs on the surface of the CNT. CNT decomposition that occurs in the temperature range of 250-500 o C is caused by the decomposition of functional groups contained in the CNT [12].…”

“…C-O-C bonds are polar ether functional groups so that they can improve the hydrophilic nature of CNT [11]. Previous researchers have performed CNT functionalization using strong acids consisting of HNO3, H2SO4, and HCl [12]. They reported that the strong acid can increase the CNT dispersibility and solubility but still cannot reduce the CNT toxicity.…”

Carbon Nanotubes in Cancer Research and Therapy

“…Unmodified, ozonized, aryl sulfonated SWCNTs exhibit no degradation under similar conditions. The observed metabolism phenomenon may be accredited to the unique chemistry of acid carboxylation, which, in addition to introduction the reactive, modifiable COOH groups onto CNT surfaces, also induces collateral damage to the tubular graphemic backbone in the form of neighboring active sites that provide points of attack for further oxidative degradation [6,7].…”