The effect of hypoxia on the levels of circulating catecholamines in the dogfishScyliorhinus canicula

Butler, Patrick J.; Taylor, E. W.; Capra, Mike; Davison, William

doi:10.1007/bf00738416

Cited by 89 publications

(20 citation statements)

References 22 publications

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“…It is evident from the studies compiled in the aforementioned review that there are marked differences in the levels of plasma catecholamines observed in different species in response to different types of stress. The dominance of either adrenaline or noradrenaline in the circulation during a stressful period is not only dependent upon storage levels [25,28,41,42,66,220] but also on the rate of metabolic degradation [56,191,192], accumulation of catecholamines into tissues [40,190,191,271,272] and the 'ability' of chromaffin cells to secrete catecholamines [239].…”

Section: Situations Eliciting Catecholamine Secretionmentioning

confidence: 99%

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The adrenergic stress response in fish: control of catecholamine storage and release

Reid

Bernier

Perry

1998

Comparative Biochemistry and Physiology Part C: Pharmacology, T

242

191

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In fish, the catecholamine hormones adrenaline and noradrenaline are released into the circulation, from chromaffin cells, during numerous 'stressful' situations. The physiological and biochemical actions of these hormones (the efferent adrenergic response) have been the focus of numerous investigations over the past several decades. However, until recently, few studies have examined aspects involved in controlling/modulating catecholamine storage and release in fish. This review provides a detailed account of the afferent limb of the adrenergic response in fish, from the biosynthesis of catecholamines to the exocytotic release of these hormones from the chromaffin cells. The emphasis is on three particular topics: (1) catecholamine biosynthesis and storage within the chromaffin cells including the different types of chromaffin cells and their varying arrangement amongst species; (2) situations eliciting the secretion of catecholamines (e.g. hypoxia, hypercapnia, chasing); (3) cholinergic and non-cholinergic (i.e. serotonin, adrenocorticotropic hormone, angiotensin, adenosine) control of catecholamine secretion. As such, this review will demonstrate that the control of catecholamine storage and release in fish chromaffin cells is a complex processes involving regulation via numerous hormones, neurotransmitters and second messenger systems.

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Section: Situations Eliciting Catecholamine Secretionmentioning

confidence: 99%

“…One of the more prevalent environmental/experimental conditions eliciting an elevation of plasma catecholamine levels is external hypoxia [14,28,36,41,89,92,138,140,177,219,225,226,231,235,239,246,268].…”

Section: Catecholamine Release During Hypoxiamentioning

confidence: 99%

The adrenergic stress response in fish: control of catecholamine storage and release

Reid

Bernier

Perry

1998

Comparative Biochemistry and Physiology Part C: Pharmacology, T

242

191

View full text Add to dashboard Cite

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“…locomotion, digestion) and for appropriate responses to environmental changes (Farrell, 2002;Claireaux et al, 2005;Gollock et al, 2006;Clark and Seymour, 2006;Steinhausen et al, 2008), and an understanding of how chronic hypoxia affects both swimming performance and cardiovascular function could reveal important information about whether fish will survive, and how well they adapt to, hypoxic environments. At present, studies on the effects of chronic (weeks of) hypoxia have been conducted on a limited number of teleost species, and focused on a range of aspects such as food intake (Chabot and Dutil, 1999;Pichavant et al, 2000;Pichavant et al, 2001;Zhou et al, 2001), reproduction (Wu et al, 2003), oxygen carrying capacity (Greaney et al, 1980;Taylor and Miller, 2001;Pichavant et al, 2003), cardiomyocyte physiology (Lennard and Huddart, 1992;Paajanen and Vornanen, 2003) and circulating catecholamine levels (Butler et al, 1979;Montpetit and Perry, 1998). However, to our knowledge only two studies (Kutty, 1968;Bushnell et al, 1984) have investigated how chronic hypoxia affects fish swimming performance and metabolism, and only one study (Burleson et al, 2002) has examined the effect of chronic hypoxia on fish in vivo cardiovascular function.…”

Section: Introductionmentioning

confidence: 99%

Effect of acute and chronic hypoxia on the swimming performance, metabolic capacity and cardiac function of Atlantic cod (Gadus morhua)

Petersen

Gamperl

2010

Journal of Experimental Biology

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SUMMARYLow water oxygen content (hypoxia) is a common feature of many freshwater and marine environments. However, we have a poor understanding of the degree to which diminished cardiac function contributes to the reduction in fish swimming performance concomitant with acute exposure to hypoxia, or how fish cardiorespiratory physiology is altered by, or adapts to, chronic hypoxia. Thus, we acclimated adult Atlantic cod (Gadus morhua) to either ~8-9kPa O 2 (40-45% air saturation) or ~21kPaO 2 (100% air saturation; normoxia) for 6-12weeks at 10°C, and subsequently measured metabolic variables [routine oxygen consumption (M O2 ), maximum M O2 , metabolic scope] and cardiac function (cardiac output, Q; heart rate, f H ; and stroke volume, V S ) in these fish during critical swimming speed (U crit ) tests performed at both levels of water oxygenation. Although surgery (flow probe implantation) reduced the U crit of normoxia-acclimated cod by 14% (from 1.74 to 1.50BLs -1 ) under normoxic conditions, exposure to acute hypoxia lowered the U crit of both groups (surgery and non-surgery) by ~30% (to 1.23 and 1.02BLs -1 , respectively). This reduction in swimming performance was associated with large decreases in maximum M O2 and metabolic scope (≥50%), and maximum f H and Q (by 16 and 22%), but not V S . Long-term acclimation to hypoxia resulted in a significant elevation in normoxic metabolic rate as compared with normoxia-acclimated fish (by 27%), but did not influence normoxic or hypoxic values for U crit , maximum M O2 or metabolic scope. This was surprising given that resting and maximum values for Q were significantly lower in hypoxia-acclimated cod at both levels of oxygenation, because of lower values for V S . However, hypoxia-acclimated cod were able to consume more oxygen for a given cardiac output. These results provide important insights into how fish cardiorespiratory physiology is impacted by short-term and prolonged exposure to hypoxia, and further highlight the tremendous capacity of the fish cardiorespiratory system to deal with environmental challenges.

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“…Increases in the catecholamine adrenaline may account for the elevated wholeblood glucose in school sharks. This has been demonstrated in nursehound (Scyliorhinus stellaris), spiny dogfish (deRoos and deRoos, 1978) and little skate (Raja erinacea; Grant et al, 1969), showing that elasmobranchs have a robust adrenergic stress response (Butler et al, 1978). Both school and gummy sharks increased Hb and Hct in response to hypersaline exposure (Table 2), suggesting haemoconcentration due to water efflux.…”

Section: Discussionmentioning

confidence: 77%

Physiological responses to hypersalinity correspond to nursery ground usage in two inshore shark species (Mustelus antarcticus & Galeorhinus galeus)

Tunnah

Mackellar

Barnett

et al. 2016

Journal of Experimental Biology

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Shark nurseries are susceptible to environmental fluctuations in salinity because of their shallow, coastal nature; however, the physiological impacts on resident elasmobranchs are largely unknown. Gummy sharks (Mustelus antarcticus) and school sharks (Galeorhinus galeus) use the same Tasmanian estuary as a nursery ground; however, each species has distinct distribution patterns that are coincident with changes in local environmental conditions, such as increases in salinity. We hypothesized that these differences were directly related to differential physiological tolerances to high salinity. To test this hypothesis, we exposed wild, juvenile school and gummy sharks to an environmentally relevant hypersaline (120% SW) event for 48 h. Metabolic rate decreased 20-35% in both species, and gill Na + /K + -ATPase activity was maintained in gummy sharks but decreased 37% in school sharks. We measured plasma ions (Na + , K + , Cl − ) and osmolytes [urea and trimethylamine oxide (TMAO)], and observed a 33% increase in plasma Na + in gummy sharks with hyperosmotic exposure, while school sharks displayed a typical ureosmotic increase in plasma urea (∼20%). With elevated salinity, gill TMAO concentration increased by 42% in school sharks and by 30% in gummy sharks. Indicators of cellular stress (heat shock proteins HSP70, 90 and 110, and ubiquitin) significantly increased in gill and white muscle in both a species-and a tissue-specific manner. Overall, gummy sharks exhibited greater osmotic perturbation and ionic dysregulation and a larger cellular stress response compared with school sharks. Our findings provide physiological correlates to the observed distribution and movement of these shark species in their critical nursery grounds.

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The effect of hypoxia on the levels of circulating catecholamines in the dogfishScyliorhinus canicula

Cited by 89 publications

References 22 publications

The adrenergic stress response in fish: control of catecholamine storage and release

The adrenergic stress response in fish: control of catecholamine storage and release

Effect of acute and chronic hypoxia on the swimming performance, metabolic capacity and cardiac function of Atlantic cod (Gadus morhua)

Physiological responses to hypersalinity correspond to nursery ground usage in two inshore shark species (Mustelus antarcticus & Galeorhinus galeus)

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