Quality of life is a complicated concept that has attracted broad attention from multiple disciplines. This article introduces a set of studies that employ diverse approaches to explore how work, vocational, and career experiences shape quality of life among migrants, and proposes a future agenda to extend this stream of research. Specifically, operationalizing quality of life in different ways, research showcased in this special issue has demonstrated how international and intranational migrants achieve, maintain, and enhance their wellbeing in different life domains. Reflecting on the literature and the showcased studies, this article proposes that future research should advance the current inquiry by better categorizing vocational experiences, uniquely operationalizing of quality of life in migration contexts, taking a more culturally sensitive perspective, and broadening methodological approaches. Abstract Quality of life is a complicated concept that has attracted broad attention from multiple disciplines. This article introduces a set of studies that employ diverse approaches to explore how work, vocational, and career experiences shape quality of life among migrants, and proposes a future agenda to extend this stream of research. Specifically, operationalizing quality of life in different ways, research showcased in this special issue has demonstrated how international and intranational migrants achieve, maintain, and enhance their well-being in different life domains. Reflecting on the literature and the showcased studies, this article proposes that future research should advance the current inquiry by better categorizing vocational experiences, uniquely operationalizing of quality of life in migration contexts, taking a more culturally sensitive perspective, and broadening methodological approaches.