The effect of infrapatellar fat pad resection on outcomes post-total knee arthroplasty: a systematic review

White, Leigh; Holyoak, Rhys; Sant, J; Hartnell, Nicholas J; Mullan, Judy

doi:10.1007/s00402-016-2440-x

Cited by 38 publications

(41 citation statements)

References 21 publications

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“…As matter of fact, IFP is well innervated: peptidergic C‐ and substance P positive nerve fibers have been found in this adipose tissue (Clockaerts et al, ; Ioan‐Facsinay and Kloppenburg, ). In 2016, two interesting systematic reviews have focused the attention on the resection/preservation of IFP during total knee replacement (TKR) (White et al, ; Ye et al, ). It has been estimated that IFP removal occurs in 88% of TKR (White et al, ), even if it still remains a matter of surgeon preference.…”

Section: Obesity and Related Comorbidities In Koamentioning

confidence: 99%

Systemic and Local Adipose Tissue in Knee Osteoarthritis

Belluzzi

Hadi

Granzotto

et al. 2017

Journal Cellular Physiology

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Osteoarthritis is a common chronic joint disorder affecting older people. The knee is the major joint affected. The symptoms of osteoarthritis include limited range of motion, joint swelling, and pain causing disability. There are no disease modifying drugs available, and treatments are mainly focused on pain management. Total knee replacement performed at the end stage of the disease is considered the only cure available. It has been found that obese people have an increased risk to develop not only knee but also hand osteoarthritis. This supports the concept that adipose tissue might be related to osteoarthritis not only through overloading. As matter of fact, obesity induces a low grade systemic inflammatory state characterized by the production and secretion of several adipocytokines that may have a role in osteoarthritis development. Furthermore, hypertension, impaired glucose, and lipid metabolism, which are comorbidities associated with obesity, have been shown to alter the joint tissue homeostasis. Moreover, infrapatellar fat pad in the knee has been demonstrated to be a local source of adipocytokines and potentially contribute to osteoarthritis pathogenesis. Here, we discuss the role of systemic and local adipose tissue in knee osteoarthritis. J. Cell. Physiol. 232: 1971-1978, 2017. © 2016 Wiley Periodicals, Inc.

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Section: Obesity and Related Comorbidities In Koamentioning

confidence: 99%

Systemic and Local Adipose Tissue in Knee Osteoarthritis

Belluzzi

Hadi

Granzotto

et al. 2017

Journal Cellular Physiology

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“…Postoperative pain is a common source of patient dissatisfaction [2]. The results of this study showed a significant reduction in postoperative pain and better recovery of post-operative knee flexion.…”

Section: Commentarymentioning

confidence: 49%

Adjuncts to Local Anaesthetics in Total Knee Arthroplasty

2017

JACCOA

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“…4 We demonstrated that the greatest benefit in reduced postoperative pain is beyond 6 months post TKA; incorporating results for one small, high quality randomised controlled trial by Pinsornsak et al 5 and two larger low quality studies. 6 7 At 5.1 years, the incidence of knee pain was almost halved in the preservation group.…”

mentioning

confidence: 73%