The effect of inpatient rehabilitation programmes on quality of life in patients with cystic fibrosis: A multi-center study

Schmitz, Tim; Goldbeck, Lutz

doi:10.1186/1477-7525-4-8

Cited by 25 publications

(6 citation statements)

References 12 publications

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“… 32 If the financial resources addressed to the health of these patients can put to better use, as different sources have proposed, we will surely contribute with better quality of life for patients with CF. 33 …”

Section: Discussionmentioning

confidence: 99%

Exames Para Avaliar a Sensibilização Ao Aspergillus Fumigatus Em Fibrose Cística

Aguiar

Damaceno

Forte³

2017

Rev. paul. pediatr.

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Objective: To evaluate the results of the tests used to identify the IgE mediated sensitization to Aspergillus fumigatus in patients with cystic fibrosis.Methods: This is a cross-sectional descriptive study with a convenience sample of 86 patients diagnosed with cystic fibrosis in the Reference Service in Cystic Fibrosis at a tertiary teaching hospital. The following tests were performed to assess the sensitization to A. fumigatus in patients with cystic fibrosis: Total serum IgE, eosinophil count, fungus detection through oropharyngeal swab or sputum culture, serum-specific IgE, and immediate-type hypersensitivity (IgE) skin tests. We compared the results of the different tests performed.Results: In 33 (38.4%) patients with cystic fibrosis, with ages ranging from 1 to 33 years (median of 8 years), the IgE-mediated A. fumigatus sensitization test results were: in 16 patients, there was an increase in serum-specific IgE (>0.35 kU/L); in 23, skin tests were positive; and six had sensitization in both tests. We observed two patients with eosinophilia (>1,000 eosinophils/mm3) and seven with increasing total serum IgE (>1,000 IU/mL), all of whom obtained negative results in skin tests and had no IgE increase specific to A. fumigatus. A. fumigatus was not detected in oropharyngeal swabs and/or sputum culture of any patients.Conclusions: We conclude that, among the tests used to assess sensitization to A. fumigatus in cystic fibrosis patients, both serum-specific IgE and immediate-type hypersensitivity (IgE) skin tests are required. Serum eosinophilia and respiratory secretion culture were not essential in this study.

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Section: Discussionmentioning

confidence: 99%

Exames Para Avaliar a Sensibilização Ao Aspergillus Fumigatus Em Fibrose Cística

Aguiar

Damaceno

Forte³

2017

Rev. paul. pediatr.

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“…Unfortunately the latter study also had a retrospective design and the completeness of the sample is not known. Problems with selection bias must also be considered in the study on the impact of the rehabilitation program on quality of life indices [ 11 ]. In that study an unknown number of patients participating in rehabilitation programs at various sites over undetermined time periods were combined.…”

Section: Discussionmentioning

confidence: 99%

“…In that study an unknown number of patients participating in rehabilitation programs at various sites over undetermined time periods were combined. Interestingly, the quality of life improved for a sustained period of at least two months after the end of the intervention [ 11 ]. A study of the site in Davos, Switzerland, which was also included in our study, reporting on 13 Israeli patients with cystic fibrosis, did not find improvement of lung function; however exercise tolerance and weight improved significantly [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Rehabilitation Programs for Cystic Fibrosis - View from a CF Center

Griese

Busch²,

Caroli³

et al. 2010

TORMJ

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Background:Rehabilitation programs are comprehensive interventions which effectively improve the health status and reduce costs in chronic respiratory illnesses. Because patients with cystic fibrosis have been discouraged to participate for concerns of microbial cross infection, the efficacy of systematic rehabilitation is unknown for this group.Methods:We retrospectively studied 142 cystic fibrosis patients aged 2-46 years who participated in rehabilitation programs taking place in Germany/Switzerland and in Israel, focusing on changes in lung function and weight.Results:During 172 stays in 97 patients in Israel and 68 stays in 45 patients rehabilitating in Germany/Switzerland, overall lung function and weight improved. Outcome did not differ between Israel and German/Swiss sites. Interestingly, lung function improved during the initial phase of the stay, whereas weight gain was sustained throughout. The study uncovered gaps in reporting sufficient individual outcome information back to the admitting centre.Conclusions:Rehabilitation programs specified for cystic fibrosis patients need to be assessed prospectively to optimize treatment of this life limiting condition.

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“…Increasing physical activity through exercise programs has been shown in multiple studies to reduce cancer symptoms such as fatigue 6-11 , cachexia 12 , and pain. 13-21 Studies have demonstrated improvement in symptoms and or quality of life during inpatient rehabilitation of several populations including patients with multiple sclerosis, 22,23 chronic obstructive pulmonary disease, 24 lung transplant patients, 25 cystic fibrosis, 26 stroke, 27 general rehabilitation 28 and cancer. 29-31 These prior studies utilized a variety of instruments to assess symptoms and function.…”

Section: Introductionmentioning

confidence: 99%

Symptom burden and functional gains in a cancer rehabilitation unit

Lee

Tran

et al. 2015

International Journal of Therapy and Rehabilitation

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Background/Aims To determine if there is a relationship between patient symptoms and functional improvement on inpatient rehabilitation. Methods Retrospective review of medical records at an American tertiary referral-based cancer center of all patients admitted to an inpatient rehabilitation unit between 3/1/2013-5/20/2013. Main outcome measures included the Edmonton Symptom and Assessment Scale (ESAS) and Functional Independence Measure (FIM). Findings The medical records for 71 unique cancer rehabilitation inpatients were analyzed. Statistical analysis of total admission ESAS on total FIM change found no significant relationships. The symptom burden of the patients was mild. Patients demonstrated statistically significant improvements in function and symptoms during inpatient rehabilitation. The mean change in total FIM and total ESAS were an increase of 19.20 and decrease of 7.41 respectively. Statistically significant changes occurred in fatigue, sleep, pain, and anxiety. Conclusion Both symptom and functional scores improved significantly during inpatient rehabilitation. However, no significant relationships were found between symptoms at admission and improvement in FIM.

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The effect of inpatient rehabilitation programmes on quality of life in patients with cystic fibrosis: A multi-center study

Abstract: Background: Disease-specific, multimodal inpatient rehabilitation programmes are designed to improve the physical, emotional, and social functioning of patients with cystic fibrosis (CF).

Cited by 25 publications

References 12 publications

Exames Para Avaliar a Sensibilização Ao Aspergillus Fumigatus Em Fibrose Cística

Exames Para Avaliar a Sensibilização Ao Aspergillus Fumigatus Em Fibrose Cística

Rehabilitation Programs for Cystic Fibrosis - View from a CF Center

Symptom burden and functional gains in a cancer rehabilitation unit

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