The effect of intramuscular administration of colistin on the development and course of experimentally induced oedema disease in weaned piglets

Abstract

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Escherichia coli strains causing edema disease in northern Vietnam share an identical verotoxin 2e

“…The mechanism how these VTEC could reach the mesenteric lymph node has remained unclear (Konstantinova et al 2008). In our study, high proportions of F18 + /VT2e + E. coli isolates (52%) were recovered from mesenteric lymph nodes which is in agreement with previous studies on E. coli causing ED in Vietnam and India, performed by Nguyen (2005) and Barman et al (2008), respectively.…”

“…Although VTEC are non-invasive extracellular bacteria, high amounts of VT2e + E. coli can be found in the mesenteric lymph nodes and in lung of euthanized pigs, which have been experimentally infected with VT2e + E. coli (Tsukahara et al 2005;Konstantinova et al 2008). The mechanism how these VTEC could reach the mesenteric lymph node has remained unclear (Konstantinova et al 2008).…”

Evaluation of the ability of colistin, amoxicillin (components of Potencil®), and fluoroquinolones to attenuate bacterial endotoxin‐ and Shiga exotoxin‐mediated cytotoxicity—In vitro studies

“…According to recent epidemiological data, swine may carry Stx2e‐producing E. coli with virulence gene profiles associated with human infections (Baranzoni et al., ; Muthing et al., ). Moreover both colistin and amoxicillin were used before against E. coli ‐ produced Stx2e (Konstantinova et al., ). Therefore, in this part of the study, the O139 ETEEC reference strain ( E. coli ATCC 23546), which releases Stx2e, was used.…”

Dominantes en pathologie porcine : la filière porcine

“…coli se multiplient dans l'intestin et les noeuds lymphatiques mésentériques et produisent une vérotoxine responsable des dommages vasculaires entraînant les oedèmes (Konstantinova et al 2007). …”