The Effect of Intravenous Hyperalimentation on Erythrocyte Lipids

Sgoutas, Demetrios S.; Jones, Rosanne

doi:10.3181/00379727-145-37861

Cited by 9 publications

(1 citation statement)

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“…feeding which was reversed by an oral dose of methyl linoleate (2% of daily calories). Sgoutas and Jones (33) and Richardson and Sgoutas (34) found an EFA deficiency in four malnourished adults after 6-8 weeks on lipid-free parenteral nutrition; oral safflower oil reversed the EFA deficiency. For perspective, the Food and Nutrition Board of the National Academy of Science-National Research Council recommends that the EFA requirement of man lies within 1-2% of the total caloric intake (35).…”

Section: Lipid Emulsions In Total Parenteral Nutritionmentioning

confidence: 95%

Some nutrient interrelations during total intravenous alimentation in adult man—A review

Wixom

Sheng

Anderson

et al. 1976

Lipids

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Selected aspects of total parenteral nutrition in man are reviewed with emphasis on carbohydrate, lipid, and hormonal interactions. In an experiment to test for the essentiality of a specific amino acid, a normal adult man received all major and minor nutrients, except lipids, by intravenous alimentation for 48 days. A chemical deficiency of essential fatty acids without clinical symptoms was promptly observed in four plasma lipid fractions and the phospholipid fraction of erythrocytes. With the glucose providing 2,600 kcal/day, blood glucose remained normal, but a hypertrigly ceridemia was observed. Plasma insulin rose and cortisol fell. To meet the essential fatty acid and energy requirements of man, critical experiments are needed to define the safe utilization of lipid emulsions during prolonged intravenous nutrition.

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Section: Lipid Emulsions In Total Parenteral Nutritionmentioning

confidence: 95%