The Effect of Intravenous Magnesium Sulfate Versus Intravenous Sufentanil on the Duration of Analgesia and Postoperative Pain in Patients with Tibia Fracture

Abstract

BackgroundIn the recent decades controlling postoperative pain has become a popular topic as it leads to the patients’ wellbeing and improved life quality, while it reduces the costs for both patients and medical facilities.ObjectivesThis study aimed at comparing intravenous magnesium sulfate versus intravenous sufentanil on the duration of analgesia and postoperative pain in patients undergoing tibia fracture surgery.MethodsThis double blind clinical trial study was performed on 70 candidates of tibia fractures between the ages of 18 and 55 years with American society of anesthesiologists (ASA) class I and II. The patients were randomly divided to 2 groups, 1 receiving magnesium sulfate (M) and another receiving sufentanil (S). Both of the groups underwent spinal anesthesia with 10 mg bupivacaine 0.5%. One hour after ensuring the sensorimotor blockade, in the S group 0.1 µg/kg/hour and in the M group 8 mg/kg/hour was diluted in 1 liter of Ringer’s solution and infused. In this study, full weakness of the lower limb was considered as the sign of sensorimotor blockade initiation. The postoperative pain intensity was measured using the Visual Analog Scale (VAS), 0, 1, 4, 8, 16, and 24 hours after the end of anesthesia duration. In case of VAS ≥ 3, the patients received 0.3 mg/kg pethidine, intravenously. At last, the time of requesting the first narcotic drug and the total usage of pethidine were recorded.Results and ConclusionsSufentanil was found to be more effective than magnesium sulfate in reducing postoperative pain and the time of first narcotics request was later in patients receiving sufentanil (P < 0.05).

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“…[1][2][3] Several methods have been used to avoid the stress response and increased IOP. One of these methods is using supraglottic airway device that is designed for the lower stimulation and prevention of injuries caused by tracheal intubation to the soft tissues, teeth, vocal cords, etc.…”

Comparison of the Ketamine-Lidocaine and Fentanyl-Lidocaine in Postoperative Analgesia in Axillary Block in Upper Limb Fractures By Ultrasound Guidance

“…Performing this block in patients with difficult airway and underlying comorbid diseases is believed to be beneficial (3). Lower hospital stay, lower financial cost, and avoidance of general anesthesia complications, postoperative analgesia, and reduced opioid use and increased patient satisfaction are remarkable benefits that can be cited in comparison to a general anesthetic for peripheral nerve blocks (4,5). The peripheral nerve blocks in the upper extremity include the interscalene, supraclavicular, infraclavicular, axillary, etc.…”

“…There-fore, it reduces complications associated with blind techniques, such as intravascular injection, hematoma, and pneumothorax (9). Local anesthetic drugs prevent the directing of electrical impulses in nervous-muscular membranes by blocking sodium channels, causing neural block and loss of sensory and motor perception (5). Lidocaine is a commonly used local anesthetics of the amino amide bunch with a median duration effect which is also used in the epidural and spinal anesthesia (10).…”