The Effect of Joint Position on the Pressure of Intra-Articular Effusion

Eyring, Edward J.; Murray, William R.

doi:10.2106/00004623-196446060-00008

Cited by 102 publications

(49 citation statements)

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“…5 c however, the observed pressure is influenced greatly by flexion or extension of the joint. The effect of position on IAP has been shown in human joints by Eyring and Murray (14). In all experiments described herein the joint was fixed at 90 ° with adhesive tape.…”

Section: Intra-articular Pressure (Iap)---iapmentioning

confidence: 93%

Crystal-Induced Inflammation in Canine Joints

McCarty

Phelps

Pyenson

1966

The Journal of Experimental Medicine

128

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The nearly constant finding of sodium urate crystals in aspirated gouty synovial fluid (1) led to the induction of acute arthritis in both human (2, 3) and canine (3) subiects by intrasynovial crystal injection. Calcium pyrophosphate crystals, identified in the synovial fluid from patients with a goutlike syndrome ("pseudogout"), and crystals of adrenocorticosteroid esters are also irritants when injected (4, 5). Crystal-induced inflammation is completely reversible, dose related, and nonspecific with regard to host or to the chemical composition of the injected crystal. These observations confirmed and extended findings recorded by His and Freudweiler at the end of the nineteenth century (6)(7)(8)).An experimental model of crystal synovitis in the dog and several methods for its quantification are described herein. Applications of these methods to the study of the host response mechanism are described in the accompanying paper (9) and in reference 10. MethodsGeneral Considerations.--The knee (stifle) joints of mongrel dogs weighing 12 to 25 kg were used. Light anesthesia was induced with intravenous sodium pentobarbital (25 to 35 mg/kg); additional small doses were given as needed for maintenance. One experiment was performed using the "physiologic" anesthetic chlorolose (50 mg/kg intravenously). Body temperature, monitored by rectal thermometer, was controlled with an electric blanket within a range of 2°C. In some experiments, the trachea was intubated and breathing was maintained with a me-*

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Section: Intra-articular Pressure (Iap)---iapmentioning

confidence: 93%

Crystal-Induced Inflammation in Canine Joints

McCarty

Phelps

Pyenson

1966

The Journal of Experimental Medicine

128

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“…Intra-articular pressure is highest when joints are fully extended. 9 Therefore, children with active JIA tend to adopt flexed postures, which can lead to contractures and soft tissue shortening. In addition, pain from increased intra-articular pressure can cause muscle inhibition and weakness.…”

Section: Consequences Of Pathophysiology Of Jiamentioning

confidence: 99%

Is hydrotherapy cost-effective? A randomised controlled trial of combined hydrotherapy programmes compared with physiotherapy land techniques in children with juvenile idiopathic arthritis

Epps¹,

Ginnelly²,

Utley³

et al. 2005

Health Technol Assess

153

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“…A decrease in the circulation of the capital femoral epiphysis has been produced experimentally in puppies by increasing the intra-articular pressure, as measured by radioisotope or vascular dye uptake (Tachdjian & No data are available on the normal intraarticular pressure of the human hip in uiuo, but the pressure of hips after tamponade has been shown to depend on the position of the joint both in patients with fractured femoral neck (Soto-Hall et al 1964) and in cadavers (Eyring & Murray 1964), with the highest pressures in internal rotation and extension. Soto-Hall et al (1964) found values of 9 and 10 kPa in two patients with "idiopathic synovial effusion" with the hip in neutral position.…”

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confidence: 99%