The effect of labor on the normal values of umbilical blood acid‐base status

Yoon, Bo Hyun; Kim, Syng Wook

doi:10.3109/00016349409006272

Cited by 20 publications

(14 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the current study, funisitis was significantly associated with MSAF, lower pH and base excess and associated with NICU admission with marginal significance. This association might be, in part, attributed to the longer duration of labor in patients with funisitis, because prolonged duration of labor was associated with lower cord pH at birth and adverse perinatal outcome in previous reports 33, 34 . However, the association between funisitis and MSAF remained significant, even after adjusting for the duration of labor (p<0.001), although the difference in cord pH at birth and the rate of NICU admission between patients with and without funisitis became insignificant after adjusting for the duration of labor.…”

Section: Discussionmentioning

confidence: 79%

The frequency and risk factors of funisitis and histologic chorioamnionitis in pregnant women at term who delivered after the spontaneous onset of labor

Lee

Romero

Lee

et al. 2010

The Journal of Maternal-Fetal & Neonatal Medicine

Self Cite

View full text Add to dashboard Cite

Objective To examine the frequency and risk factors of funisitis and histologic chorioamnionitis in the placentas of term pregnant women who delivered after the spontaneous onset of labor. Methods The frequency of funisitis and histologic chorioamnionitis was examined in consecutive pregnant women at term with singleton pregnancies who delivered after the spontaneous onset of labor. Nonparametric statistics were used for data analysis. Results 1) The frequency of funisitis and histologic chorioamnionitis was 6.7% (88/1316) and 23.6% (310/1316), respectively; 2) Patients with funisitis had significantly higher rates of nulliparity, regional analgesia, operative vaginal delivery, longer duration of labor and rupture of membranes (ROM), and higher gestational age and birthweight than those without funisitis (p<0.05 for each); 3) Patients with histologic chorioamnionitis had significantly higher rates of nulliparity, oxytocin augmentation, regional analgesia, cesarean section or operative vaginal delivery, longer duration of labor and ROM, and higher gestational age and birthweight than those without histologic chorioamnionitis (p<0.05 for each); 4) Multiple logistic regression analysis indicated that the longer duration of labor, the higher the risk of funisitis, and that nulliparity and longer duration of labor significantly increased the odds of histologic chorioamnionitis (p<0.05 for each). Conclusion The longer the duration of labor, the higher the risk of funisitis and histologic chorioamnionitis in pregnant women at term who delivered after the spontaneous onset of labor.

show abstract

Section: Discussionmentioning

confidence: 79%

The frequency and risk factors of funisitis and histologic chorioamnionitis in pregnant women at term who delivered after the spontaneous onset of labor

Lee

Romero

Lee

et al. 2010

The Journal of Maternal-Fetal & Neonatal Medicine

Self Cite

View full text Add to dashboard Cite

show abstract

“…Furthermore, we carefully selected a homogenous group of twin pregnancies without any maternal or fetal complications. Consequently, many of the confounding variables that might affect cord blood gas values, such as, labor, mode of delivery, and epidural anesthesia, were eliminated (24, 25). …”

Section: Discussionmentioning

confidence: 99%

Relationship between Twin-to-twin Delivery Interval and Umbilical Artery Acid-base Status in the Second Twin

et al. 2007

Self Cite

View full text Add to dashboard Cite

The purpose of this study was to determine the effect of twin-to-twin delivery interval on umbilical artery acid-base status of the second twin at birth. This was a retrospective cohort study of all live-born twins with measured acid-base status in umbilical arterial blood who were delivered after 34 weeks' gestation from June 2003 to February 2006. Twins with any maternal or fetal complications were excluded. Subjects were divided into two groups based on the mode of delivery of the first twin: normal cephalic vaginal deliveries (n=40) or cesarean deliveries (n=67). The inter-twin differences in umbilical arterial blood pH, PCO2, PO2, and base excess in twin newborns born vaginally were significantly greater than the corresponding differences in those born by cesarean section. A significant positive correlation was found between twin-to-twin delivery interval and inter-twin difference in umbilical arterial blood pH in twin newborns born vaginally. The umbilical arterial blood pH of the second twin was less than 7.0 in 14% (2/14) in cases delivered more than 20 min after the first twin. The umbilical arterial blood gas status of the second twin worsened with increasing twin-to-twin delivery interval, and pathologic fetal acidemia (pH < 7.0) might develop in the second twin when the twin-to-twin delivery interval was greater than 20 min.

show abstract

“…This demonstrates that there is a large reserve for protecting the fetus from acidosis. [26][27][28] Ephedrine, with its longer duration of action, still has a role in obstetric anesthesia to prevent or treat spinal-induced hypotension when given in an appropriate dose. The optimal method to administer ephedrine, whether combined with other vasopressor therapy or nonmedication therapy, awaits future study.…”

Section: Ephedrine and Umbilical Arterial Acidosismentioning

confidence: 99%

Obstetric Anesthesia Controversies: Vasopressor Choice for Postspinal Hypotension During Cesarean Delivery

Macarthur

Riley

2007

International Anesthesiology Clinics

View full text Add to dashboard Cite

The effect of labor on the normal values of umbilical blood acid‐base status

Abstract: There is a significant fall in umbilical artery pH and bicarbonate with the presence of labor and increased duration of second stage of labor in healthy term neonates. This should be taken into consideration in evaluating neonatal well-being by cord blood pH and acid-base measurements.

Cited by 20 publications

References 32 publications

The frequency and risk factors of funisitis and histologic chorioamnionitis in pregnant women at term who delivered after the spontaneous onset of labor

The frequency and risk factors of funisitis and histologic chorioamnionitis in pregnant women at term who delivered after the spontaneous onset of labor

Relationship between Twin-to-twin Delivery Interval and Umbilical Artery Acid-base Status in the Second Twin

Obstetric Anesthesia Controversies: Vasopressor Choice for Postspinal Hypotension During Cesarean Delivery

Contact Info

Product

Resources

About