Asparagus is a potential greenhouse crop, and its production is considerably affected by temperature and light, especially in the summer season. This study investigated the effects of the application of near-infrared (NIR)-reflective diffusion coating on a simple plastic greenhouse on microclimatic conditions, plant response, spear yield, and quality of the asparagus plant in central Taiwan. The results showed that NIR-reflective diffusion coating reduced the mean air temperature inside the greenhouse by 0.3 to 0.9 °C and leaf temperature by 2.3, 2.4, and 2.4 °C at a canopy height of 50, 100, and 50 cm, respectively. Although the accumulated daily light integral (DLI) transmitted in the coated greenhouse exhibited an 18.9% reduction compared with a 16.8% reduction in the noncoated greenhouse, a more uniform spatial light distribution was noted. Therefore, photosynthesis improved in the middle and bottom canopy, and plants could maintain a higher transpiration rate, thus resulting in atmospheric cooling. The average spear yield increased by 31.4% in summer and by 10.1% during the following harvest with a lower crude fiber (CF) content and higher Ca as well as Mg contents. In addition, the number of newly emerged shoots increased by 48.8% after the removal of the mother stalk under coating. NIR-reflective diffusion coating can be used as an energy-saving method for enhancing cooling and improving light use efficiency, thus increasing asparagus production in a greenhouse in summer.