The Effect of Low-Intensity Shock Wave Therapy on Moderate Erectile Dysfunction: A Double-Blind, Randomized, Sham-Controlled Clinical Trial

Kalyvianakis, D.; Mykoniatis, Ioannis; Pyrgidis, Nikolaos; Kapoteli, Paraskeui; Zilotis, Filimon; Fournaraki, Agrippina; Hatzichristou, Dimitrios

doi:10.1097/ju.0000000000002684

Cited by 23 publications

(11 citation statements)

References 32 publications

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“…Of these, low intensity shock wave therapy (LI‐SWT) aims to restore the erectile mechanism by delivering shock waves to the penis, which cause mechanical stress and microtrauma thereby eliciting the release of angiogenic factors that trigger neovascularization (Gruenwald et al, 2013). Though not yet approved by the Food and Drug Administration (FDA), recent work has demonstrated a potential improvement in patient‐reported erectile function scores in men undergoing treatment with LI‐SWT (Fode et al, 2017; Kalyvianakis et al, 2022). Specifically, LI‐SWT is shown to be most effective in men with vasculogenic ED (Kalyvianakis et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

“…Though not yet approved by the Food and Drug Administration (FDA), recent work has demonstrated a potential improvement in patient‐reported erectile function scores in men undergoing treatment with LI‐SWT (Fode et al, 2017; Kalyvianakis et al, 2022). Specifically, LI‐SWT is shown to be most effective in men with vasculogenic ED (Kalyvianakis et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

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Assessing the quality and readability of online content on shock wave therapy for erectile dysfunction

et al. 2022

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Patients are becoming increasingly reliant on online platforms for obtaining health information. Previous research has shown that the quality of information available on the internet regarding novel medical therapies is generally poor and frequently misleading. Shock wave therapy represents a novel restorative therapy for erectile dysfunction (ED) that has recently gained attention. We hypothesised that online sources regarding shock wave therapy for ED would be fraught with misleading claims and unreliable health information. Our objective was to evaluate the quality and readability of online medical information on shock wave therapy as a treatment for ED. Websites were generated using a Google search of ‘shock wave therapy for erectile dysfunction’ with location filters disabled. Readability was analysed using the Readable software (http://readable.com, Horsham, United Kingdom). Quality was assessed independently by three reviewers using the DISCERN tool. Articles were subdivided into those from private clinic websites and those from universities or news media websites. Statistical analysis was conducted using the Student's t test. Nine articles that resulted from the Google search had mean readability scores as follows: Flesch–Kincaid grade level (10.8), Gunning–Fog Index (13.67), Coleman–Liau Index (12.74), Simple Measure of Gobbledygook (SMOG) Index (13.33), FORCAST Grade Level (11.33), and Automated Readability Index (11.08). The mean Flesch Reading Ease score was 46.4. The articles had a mean DISCERN score of 3.1, suggesting ‘moderate quality’ content. Articles from universities (n = 2) or news sources (n = 3) had significantly higher DISCERN scores than articles from private medical practices (n = 4). There was no difference in readability scores between the groups. Articles from private clinics are just as readable as those from universities or news media, but they are significantly more biased and misleading. The current online material relating to shock wave therapy for ED may not adequately inform patients in their medical decisions making, thereby necessitating closer collaboration between the sources disseminating information and urologists.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Assessing the quality and readability of online content on shock wave therapy for erectile dysfunction

et al. 2022

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“…This very interesting article by Kalyvianakis et al, ( 6 ) offers another step in our long journey ahead. Through a double-blind, randomized clinical trial controlled by Sham, the effect of Low Intensity Shockwave Therapy on moderate erectile dysfunction was evaluated.…”

Section: Commentmentioning

confidence: 93%

Editorial Comment: The effect of low-intensity shock wave therapy on moderate erectile dysfunction: A double-blind, randomized, sham-controlled clinical trial

Vieiralves¹

2023

Int. braz j urol.

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“…3 Although the exact mechanism by which LI-SWT plays a regenerative role in ED has not been concretely defined, there is evidence that its effects are due to improved endothelial function, regeneration of nerve fibers, angiogenesis, and corporal tissue remodeling. 4,5 This is a result of shock waves producing microbubbles, which induce sheer stress that activates biological pathways that cause increased expression of growth factors. 4 There is an important distinction that must be made between shock waves and radial waves, which are both advertised for their use in ED.…”

Section: Regenerative Therapiesmentioning

confidence: 99%

Regenerative Therapy in Sexual Medicine: The Hard Facts

et al. 2023

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The Effect of Low-Intensity Shock Wave Therapy on Moderate Erectile Dysfunction: A Double-Blind, Randomized, Sham-Controlled Clinical Trial

Cited by 23 publications

References 32 publications

Assessing the quality and readability of online content on shock wave therapy for erectile dysfunction

Assessing the quality and readability of online content on shock wave therapy for erectile dysfunction

Editorial Comment: The effect of low-intensity shock wave therapy on moderate erectile dysfunction: A double-blind, randomized, sham-controlled clinical trial

Regenerative Therapy in Sexual Medicine: The Hard Facts

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