The effect of luteal phase gonadotropin-releasing hormone antagonist administration on IVF outcomes in women at risk of OHSS

Eftekhar, Maryam; Miraj, Sepideh; Mortazavifar, Zahrasadat

doi:10.29252/ijrm.14.8.507

Cited by 10 publications

(7 citation statements)

References 18 publications

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“…Reducing the rate of sever ovarian hyperstimulation syndrome (OHSS) is one of the ideal goals of controlled ovarian hyperstimulation (COH) in assisted reproduction technology (ART) programs ( 1 , 2 ). Gonadotropin-releasing hormone agonists (GnRH-a) was used for triggering oocyte maturation for OHSS prevention increasingly.…”

Section: Introductionmentioning

confidence: 99%

Final follicular maturation by administration of GnRH agonist plus HCG versus HCG in normal responders in ART cycles: An RCT

Eftekhar

Mojtahedi

Miraj

et al. 2017

IJRM

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Background:Gonadotropin-releasing hormone agonists (GnRH-a) was increasingly used for triggering oocyte maturationfor the prevention of ovarian hyperstimulation syndrome. Studies suggest that GnRH-a might be used as a better trigger agent since it causes both Luteinizing hormone and follicle stimulating hormone release from a physiologic natural cycle.Objective:The aim of this study was to evaluate the effect of dual-triggering in assisted reproductive technology outcomes.Materials and Methods:192 normal responder women aged ≤42 years and 18< Body Mass Index <30 kg/m2 enrolled in this single-blind randomized controlled trial. All participants received antagonist protocol. For final triggering, women randomly were divided into two groups. Group, I was triggered by 6500 IU human chorionic gonadotropin (hCG) alone, and group II by 6500 IU hCG plus 0.2 mg of triptorelin. The implantation, chemical, clinical and ongoing pregnancy, and abortion rates were measured.Results:The mean of retrieved oocytes and obtained embryos were statistically higher in the dual-trigger group (group I), but the implantation and pregnancy rates were similar in two groups.Conclusion:The results of our study did not confirm the favorable effect of dual-triggered oocyte maturation with a GnRH-a and a standard dosage of hCG as an effective strategy to optimize pregnancy outcome for normal responders in GnRH-antagonist cycles. We think that this new concept requires more studies before becoming a universal controlled ovarian hyperstimulation protocol in in vitro fertilization practice.

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Section: Introductionmentioning

confidence: 99%

Final follicular maturation by administration of GnRH agonist plus HCG versus HCG in normal responders in ART cycles: An RCT

Eftekhar

Mojtahedi

Miraj

et al. 2017

IJRM

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“…1 –11 In traditional medicine, folk people used medicinal plants in diverse manners to treat diseases. 12 –24 Traditional medicine is popular in all regions of the world, and its use is rapidly expanding even in developed countries. 25 –35 For example, in China, traditional herbal preparations account for 30% to 50% of the total medicinal consumption, and now the annual global market for herbal medicine is over US$60 billion.…”

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confidence: 99%

Melissa officinalis L: A Review Study With an Antioxidant Prospective

Miraj

Rafieian-Kopaei

Kiani

2016

J Evid Based Complementary Altern Med

160

111

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Melissa officinalis is a plant cultivated in some parts of Iran. The leaves of lemon balm, Melissa officinalis L (Lamiaceae), are used in Iranian folk medicine for their digestive, carminative, antispasmodic, sedative, analgesic, tonic, and diuretic properties, as well as for functional gastrointestinal disorders. This review article was aimed not only to introduce Melissa officinalis (its growth condition, its chemical compounds, and its traditional usages) but also to overview its antioxidant properties in detail. This review was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases up to 2016. The search terms used were " Melissa officinalis L," "antioxidant properties," oxidative stress," "oxidative damage", "ROS." Articles whose full texts were not available were excluded from the study. In this study, firstly, traditional usage of this herb was reviewed, including antimicrobial activity (antiparasitic, antibacterial, antiviral, etc), antispasmodic, and insomnia properties. Then, its antioxidant properties were overviewed. Various studies have shown that Melissa officinalis L possesses high amount of antioxidant activity through its chemical compounds including high amount of flavonoids, rosmaric acid, gallic acid, phenolic contents. Many studies confirmed the antioxidative effects of Melissa officinalis; thus, its effect in preventing and treating oxidative stress-related diseases might be reliable.

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“…The expert surgeon can perform laparoscopy safely and entirely via mini-Pfannenstiel incision (54, 55). …”

Section: Resultsmentioning

confidence: 99%

Single-incision laparoscopy surgery: a systematic review

Far¹,

Miraj²

2016

Electron physician

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BackgroundLaparoscopic surgery is a modern surgical technique in which operations are performed far from their location through small incisions elsewhere in the body.ObjectiveThis systematic review is aimed to overview single-incision laparoscopy surgery.MethodsThis systematic review was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases. The initial search strategy identified about 87 references. In this study, 54 studies were accepted for further screening and met all our inclusion criteria [in English, full text, therapeutic effects of single-incision laparoscopy surgery and dated mainly from the year 1990 to 2016]. The search terms were “single-incision,” “surgery,” and “laparoscopy.”ResultsSingle-incision laparoscopy surgery is widely used for surgical operations in cholecystectomy, sleeve gastrectomy, cholecystoduodenostomy, hepatobiliary disease, colon cancer, obesity, appendectomy, liver surgery, rectosigmoid cancer, vaginal hysterectomy, vaginoplasty, colorectal lung metastases, pyloroplasty, endoscopic surgery, hernia repair, nephrectomy, rectal cancer, colectomy and uterus-preserving repair, bile duct exploration, ileo-ileal resection, lymphadenectomy, incarcerated inguinal hernia, anastomosis, congenital anomaly, colectomy for cancer.ConclusionBased on the findings, single-incision laparoscopy surgery is a scarless surgery with minimal access. Although it possesses lots of benefits, including less incisional pain and scars, cosmesis, and the ability to convert to standard multiport laparoscopic surgery, it has some disadvantages, for example, less freedom of movement, fewer number of ports that can be used, and the proximity of the instruments to each other during the operation.

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The effect of luteal phase gonadotropin-releasing hormone antagonist administration on IVF outcomes in women at risk of OHSS

Cited by 10 publications

References 18 publications

Final follicular maturation by administration of GnRH agonist plus HCG versus HCG in normal responders in ART cycles: An RCT

Final follicular maturation by administration of GnRH agonist plus HCG versus HCG in normal responders in ART cycles: An RCT

Melissa officinalis L: A Review Study With an Antioxidant Prospective

Single-incision laparoscopy surgery: a systematic review

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