The Effect of Major Depression on Functional Status in Patients with Coronary Artery Disease

Abstract

The presence of major depression was associated with functional disability in patients with CAD. Further research is needed to clarify whether antidepressant treatment significantly impacts both affective symptoms and functional status in patients with coronary heart disease.

Relationship of Depression to Increased Risk of Mortality and Rehospitalization in Patients With Congestive Heart Failure

“…This finding could explain reports of greater somatic symptoms 28,29 and diminished functional status 27 in patients with depression. Patients with depression have been reported to have poor social contacts and support networks 10,[30][31][32][33][34] and to be noncompliant with treatment, 35,36 which could adversely affect outcomes. Evidence suggests that platelet activity is high in patients with depression, especially those with concomitant vascular dis- eases.…”

Assessment of anxiety and depression in hospitalized cardiac patients of Faisalabad Institute of Cardiology, Pakistan

“…Depression and anxiety are very common among patients having cardiac problems, and in a study involving patients above 30,000, it was reported that 9.3 % ambulatory cardiac patients showed depression while control showed 4.8 % [2,3,4]. It is important to detect and treat depression in Coronary Artery Disease (CAD) and post-MI patients, as the risk of a cardiac event doubles within 1 to 2 years after an MI [5,6].…”

Naturalistic outcomes of minor and subsyndromal depression in older primary care patients

“…Major depression in many settings is powerfully associated with worsened functional disability in domains including occupational, social, and more basic ADLs such as shopping, dressing, and bathing (Beekman et al, 1997;Koenig and George, 1998;Bruce, 1999;Steffens et al, 1999c;Sinclair et al, 2001;Charney et al, 2003;Noel et al, 2004). However, these studies rarely have focused on primary care elderly, or have been limited to subject selfreported data.…”