The effect of mate tea (Ilex paraguariensis) on metabolic and inflammatory parameters in high-fat diet-fed Wistar rats

Abstract

This study investigated the effects of mate tea (Ilex paraguariensis) aqueous extract consumption on metabolic indicators and inflammatory response of peritoneal macrophages in rats fed a high-fat diet (HFD). Male Wistar rats were fed a control diet or a HFD for 12 weeks. At the end of this period, rats received, or not, daily doses of yerba maté for 4 weeks. The consumption of yerba maté promoted weight loss, attenuated the HFD-detrimental effects on adiposity and insulin sensitivity and decreased blood levels of the inflammatory biomarkers (p < 0.05). Concerning peritoneal macrophages, mate tea consumption decreased the production of interleukin (IL)-6, but did not influence the production of IL-1β, tumour necrosis factor-α and nitric oxide; cytokine mRNA expression; or the activation of the nuclear factor-κB signalling pathway. In summary, the consumption of mate tea had no consistent effect in the inflammatory response of peritoneal macrophages, but reduced cardiometabolic risk markers.

Effects of mate tea consumption on muscle strength and oxidative stress markers after eccentric exercise

“…For example, MT intake has improved gene expression and activity of antioxidant enzymes in leucocytes (14,15) . MT has also reduced cytokine expression in macrophages (31) as well as inhibited neutrophil and macrophage infiltration into injured tissue (32) . After EEIDM, ) trials.…”

Bioactive Micronutrients in Coffee: Recent Analytical Approaches for Characterization and Quantification

“…Caffeine is found in many natural and processed products. Examples of these sources include green tea [30, 31], mate tea [32, 33], chocolate [34], and caffeinated beverages and energy drinks [35–37]. C. arabica [38] and Robusta coffee ( C. canephora var.…”

Yerba mate aqueous extract improves the oxidative and inflammatory states of rats with adjuvant-induced arthritis

“…4,5 Similarly, yerba mate should equally be able to attenuate the inflammatory state if one takes into account its well documented anti-inflammatory activity. [13][14][15] Considering the antioxidant and anti-inflammatory properties of yerba mate, we decided to investigate the effects of a hot water aqueous extract on both the oxidative and inflammatory states of rats with arthritis induced by the complete Freund's adjuvant as a continuation of our previous investigations on the chemical composition of hot and cold water extracts of this plant. 4,5 The hot water extract corresponds to the traditional beverage known as "chimarrão" in Brazil and simply "mate" in Spanish speaking countries.…”