The effect of mefenamic acid and ginger on pain relief in primary dysmenorrhea: a randomized clinical trial

Abstract

Ginger is as effective as mefenamic acid on pain relief in primary dysmenorrhea. Ginger does not have adverse effects and is an alternative treatment for primary dysmenorrhea.

Efficacy of Ginger for Alleviating the Symptoms of Primary Dysmenorrhea: A Systematic Review and Meta-analysis of Randomized Clinical Trials

“…Finally, 7 RCTs met the inclusion criteria after removing 3 non-RCT studies (Figure 1). The 7 RCTs were used for the systematic review [23][24][25][26][27][28][29]. The main data from included RCTs were summarized in Table 1.…”

Herbal Medicines in Idiopathic Heavy Menstrual Bleeding: A Systematic Review

“…In a clinical trial by Shirvani et al (2015), the effect of ginger on dysmenorrhea was demonstrated. The cause of pain from primary dysmenorrhea is uterine contraction and ischemia as a result of the excessive production of prostaglandins in the endometrium during ovulation.…”

“…Ginger compounds include various substances, such as gingerols, gingerdiones, beta carotene, capsaicin, caffeic acid, and curcumin. The effect of ginger on dysmenorrhea occurs via its gingerol and gingerdione compounds (Shirvani et al, 2015).…”

Ingwer: Gewürz und Arzneipflanze - wenig bekannte und unterschätzte therapeutische Eigenschaften

“…Zu einem ähnlichen Resultat gelangten Shiravani et al [34], die in einer RCT-Vergleichsstudie die Wirksamkeit von Ingwer (4 × 250 mg/Tag) mit Mefenaminsäure (3 × 250 mg/Tag) verglichen. Ingwer erwies sich also ebenso wirksam zur Behandlung von Dysmenorrhö wie das Standardpräparat Mefenaminsäure.…”