The effect of metformin on pregnancy outcome among filipino women with polycystic ovary syndrome

Abstract

BACKGROUND The use of me*ormin in PCOS is increasingly accepted but its therapeu;c use during pregnancy is s;ll a debatable issue. There are few local studies on the use of me*ormin among PCOS pa;ents and data is lacking among Filipinos. OBJECTIVES To determine the effect of me*ormin on maternal and neonatal outcome among pregnant Filipino women with PCOS. METHODOLOGY DESIGN: Retropsec;ve Cohort Study • Outcome Measures: Maternal outcome-rate of first trimester spontaneous abor;on, development of gesta;onal diabetes, pregnancy-induced hypertension, mode of delivery and gesta;onal age of delivery. Neonatal outcome-live birth rates, APGAR score, infants birth weight and development of congenital anomaly.