The Effect of Midday Moderate-Intensity Exercise on Postexercise Hypoglycemia Risk in Individuals With Type 1 Diabetes

Davey, Raymond J.; Howe, Warwick; Paramalingam, Nirubasini; Ferreira, Luis D.; Davis, Elizabeth A.; Fournier, Paul A.; Jones, Timothy W.

doi:10.1210/jc.2013-1169

Cited by 57 publications

(51 citation statements)

References 32 publications

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“…In a euglycemic clamp in which exercise was performed in the afternoon (4 p.m.), MacMahon et al [53] showed that glucose infusion rates necessary to maintain stable glycemia peaked in a biphasic manner: during exercise and early recovery, plus in the night afterwards (midnight to 4 a.m.). Conversely, in an otherwise equivalent design with exercise performed at midday, Davey et al [54] did not observe the same biphasic behavior in the glucose infusion rates, which were elevated for 11 h postexercise. It is difficult to draw solid conclusions in this regard from the included studies: all but three experiments were carried out in the morning; with the exceptions of Maran et al [33] (exercise at approximately 2 p.m.), Iscoe and Riddell [31], and Yardley et al [28] (both at 5 p.m).…”

Section: Strengths and Limitationsmentioning

confidence: 86%

Quantifying the Acute Changes in Glucose with Exercise in Type 1 Diabetes: A Systematic Review and Meta-Analysis

et al. 2015

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Background The acute impact of different types of physical activity on glycemic control in type 1 diabetes has not been well quantified. Objectives Our objective was to estimate the rate of change (RoC) in glucose concentration induced acutely during the performance of structured exercise and at recovery in subjects with type 1 diabetes. .70 mmol/L h" 1 (p = 0.46, 95 % CI -1.14 to +2.54) for CONT vs. REST; RoC E -5.25 mmol/ L-h" 1 (p < 0.00001, 95 % CI -7.02 to -3.48) and RoC R +0.72 mmol/L h" 1 (p = 0.71, 95 % CI -3.10 to +4.54) for IHE vs. REST; RoC E -2.61 mmol/L h _1 (p = 0.30, 95 % CI -7.55 to +2.34) and RoC R -0.02 mmol/L h _1 (p = 1.00,95 % CI -7.58 to +7.53) for RESIST vs. REST. Conclusions Novel RoC magnitudes ROCE, ROC R reflected rapid decays of glycemia during CONT exercise and gradual recoveries immediately afterwards. RESIST showed more constrained decays, whereas discrepancies were found for IHE.Novel glycemia rate-of-change magnitude data expressed in measurable units may provide a means of translating the effects of exercise on glucose dynamics into information that benefits patient self-management.Rapid decays of glycemia were found during continuous moderate exercise, followed by mild increases immediately afterwards.Resistance exercise was associated with more constrained decreases, whereas discrepancies were found for intermittent high-intensity exercise.

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Section: Strengths and Limitationsmentioning

confidence: 86%

Quantifying the Acute Changes in Glucose with Exercise in Type 1 Diabetes: A Systematic Review and Meta-Analysis

et al. 2015

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“…The effect of physical exercise on the severity and risk of hypoglycaemia was a subject of few literature reports only [31][32][33].…”

Section: Discussionmentioning

confidence: 99%

Ocena częstości występowania hipoglikemii w zależności od aktywności fizycznej

Zielińska

Bysiak-Korus

Sosna-Kondera

et al. 2018

Clinical Diabetology

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“…It could also be speculated that the anticipation to changing glucose levels is complicated by prolonged exercise. For example, the insulin-to-carbohydrate ratio required to maintain euglycemia is strongly altered during and following exercise [26]. Inadequate adjustment of pre-and post-exercise insulin use could result in exaggerated up-or downward glucose excursions [9].…”

Section: Discussionmentioning

confidence: 99%

Glycemic control during consecutive days with prolonged walking exercise in individuals with type 1 diabetes mellitus

Dijk

Eijsvogels

Nyakayiru

et al. 2016

Diabetes Research and Clinical Practice

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Running title: prolonged physical activity in type 1 diabetes Word count abstract: 239Word count main text: 3182 Tables: 1 Figures: 4 Trial number: NTR4061, www.trialregister.nl ABSTRACT Aims: Despite its general benefits for health, exercise complicates the maintenance of stable blood glucose concentrations in individuals with type 1 diabetes. The aim of the current study was to examine changes in food intake, insulin administration, and 24-h glycemic control in response to consecutive days with prolonged walking exercise (~8 h daily) in individuals with type 1 diabetes. Methods:Ten individuals with type 1 diabetes participating in the worlds' largest walking event were recruited for this observational study. Simultaneous measurements of 24-h glycemic control (continuous glucose monitoring), insulin administration and food intake were performed during a non-walking day (control) and during three subsequent days with prolonged walking exercise (daily distance 40 or 50 km). Results:Despite an increase in daily energy (31±18%; p<0.01) and carbohydrate (82±71g; p<0.01) intake during walking days, subjects lowered their insulin administration by 26±16% relative to the control day (p<0.01). Average 24-h blood glucose concentrations, the prevalence of hyperglycemia (blood glucose >10 mmol/L) and hypoglycemia (blood glucose <3.9 mmol/L) did not differ between the control day and walking days (p>0.05 for all variables). The prolonged walking exercise was associated with a modest increase in glycemic variability compared with the control day (p<0.05). Conclusion:Prolonged walking exercise allows for profound reductions in daily insulin administration in persons with type 1 diabetes, despite large increments in energy and carbohydrate intake. When taking such adjustments into account, prolonged moderate-intensity exercise does not necessarily impair 24-h glycemic control.

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The Effect of Midday Moderate-Intensity Exercise on Postexercise Hypoglycemia Risk in Individuals With Type 1 Diabetes

Cited by 57 publications

References 32 publications

Quantifying the Acute Changes in Glucose with Exercise in Type 1 Diabetes: A Systematic Review and Meta-Analysis

Quantifying the Acute Changes in Glucose with Exercise in Type 1 Diabetes: A Systematic Review and Meta-Analysis

Ocena częstości występowania hipoglikemii w zależności od aktywności fizycznej

Glycemic control during consecutive days with prolonged walking exercise in individuals with type 1 diabetes mellitus

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