the characteristics of agrochemical and physico-chemical properties of gray forest soils of Yenisei Siberia and their changes during long-term agricultural use, as well as the results of field experiments on the use of mineral fertilizers on these soils, showing their productive capacity, are presented. In the agro-gray soils of the subtaiga zone, acidification and depletion of the soil absorbing complex by exchange bases occur during their long-term use. The application of mineral fertilizers allows to increase the productivity of crop rotation by 35-69%, depending on the dose of NPK. The agro-gray soils of the subtaiga zone of Yenisei Siberia can serve as a reserve for the expansion of agricultural land in the region.